Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | RVH-421 | 0.0316 | uM | 72 | hr | 9777 | 344 | 1.0809 | 1.0084 | 0.0352 | 0.0338 | 2 |
| PLX-4720 | RVH-421 | 0.0316 | uM | 72 | hr | 8466 | 294 | 0.9364 | 1.0084 | 0.0347 | 0.0338 | 3 |
| PLX-4720 | RVH-421 | 0.0316 | uM | 72 | hr | 9001 | 259 | 1.0017 | 1.0084 | 0.0288 | 0.0338 | 4 |
| PLX-4720 | RVH-421 | 0.1000 | uM | 24 | hr | 1635 | 64 | 1.1365 | 1.0529 | 0.0391 | 0.0520 | 1 |
| PLX-4720 | RVH-421 | 0.1000 | uM | 24 | hr | 1433 | 93 | 0.9694 | 1.0529 | 0.0649 | 0.0520 | 2 |
| PLX-4720 | RVH-421 | 0.1000 | uM | 24 | hr | 3 | ||||||
| PLX-4720 | RVH-421 | 0.1000 | uM | 24 | hr | 4 | ||||||
| PLX-4720 | RVH-421 | 0.1000 | uM | 48 | hr | 1907 | 93 | 0.9478 | 0.9389 | 0.0488 | 0.0500 | 1 |
| PLX-4720 | RVH-421 | 0.1000 | uM | 48 | hr | 1563 | 94 | 0.7676 | 0.9389 | 0.0601 | 0.0500 | 2 |
| PLX-4720 | RVH-421 | 0.1000 | uM | 48 | hr | 2041 | 90 | 1.0194 | 0.9389 | 0.0441 | 0.0500 | 3 |
| PLX-4720 | RVH-421 | 0.1000 | uM | 48 | hr | 2050 | 96 | 1.0210 | 0.9389 | 0.0468 | 0.0500 | 4 |
| PLX-4720 | RVH-421 | 0.1000 | uM | 72 | hr | 8109 | 303 | 0.8945 | 0.8903 | 0.0374 | 0.0375 | 1 |
| PLX-4720 | RVH-421 | 0.1000 | uM | 72 | hr | 8731 | 293 | 0.9669 | 0.8903 | 0.0336 | 0.0375 | 2 |
| PLX-4720 | RVH-421 | 0.1000 | uM | 72 | hr | 7527 | 301 | 0.8280 | 0.8903 | 0.0400 | 0.0375 | 3 |
| PLX-4720 | RVH-421 | 0.1000 | uM | 72 | hr | 7915 | 308 | 0.8717 | 0.8903 | 0.0389 | 0.0375 | 4 |
| PLX-4720 | RVH-421 | 0.3160 | uM | 24 | hr | 1543 | 84 | 1.0555 | 1.0544 | 0.0544 | 0.0578 | 1 |
| PLX-4720 | RVH-421 | 0.3160 | uM | 24 | hr | 1551 | 95 | 1.0533 | 1.0544 | 0.0613 | 0.0578 | 2 |
| PLX-4720 | RVH-421 | 0.3160 | uM | 24 | hr | 3 | ||||||
| PLX-4720 | RVH-421 | 0.3160 | uM | 24 | hr | 4 | ||||||
| PLX-4720 | RVH-421 | 0.3160 | uM | 48 | hr | 1491 | 80 | 0.7373 | 0.7320 | 0.0537 | 0.0580 | 1 |
| PLX-4720 | RVH-421 | 0.3160 | uM | 48 | hr | 1440 | 88 | 0.7064 | 0.7320 | 0.0611 | 0.0580 | 2 |
| PLX-4720 | RVH-421 | 0.3160 | uM | 48 | hr | 1512 | 79 | 0.7487 | 0.7320 | 0.0522 | 0.0580 | 3 |
| PLX-4720 | RVH-421 | 0.3160 | uM | 48 | hr | 1506 | 98 | 0.7357 | 0.7320 | 0.0651 | 0.0580 | 4 |
| PLX-4720 | RVH-421 | 0.3160 | uM | 72 | hr | 6381 | 283 | 0.6988 | 0.6782 | 0.0444 | 0.0466 | 1 |
| PLX-4720 | RVH-421 | 0.3160 | uM | 72 | hr | 6750 | 311 | 0.7378 | 0.6782 | 0.0461 | 0.0466 | 2 |