Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
PLX-4720 SKMEL28 0.0032
uM
 48
hr
 1186 32 0.6873 0.8243 0.0270 0.0324 2
PLX-4720 SKMEL28 0.0032
uM
 48
hr
 1596 46 0.9232 0.8243 0.0288 0.0324 3
PLX-4720 SKMEL28 0.0032
uM
 48
hr
 1606 55 0.9238 0.8243 0.0342 0.0324 4
PLX-4720 SKMEL28 0.0032
uM
 72
hr
 1218 57 0.8709 0.9731 0.0468 0.0401 1
PLX-4720 SKMEL28 0.0032
uM
 72
hr
 1337 67 0.9527 0.9731 0.0501 0.0401 2
PLX-4720 SKMEL28 0.0032
uM
 72
hr
 1380 46 1.0007 0.9731 0.0333 0.0401 3
PLX-4720 SKMEL28 0.0032
uM
 72
hr
 1468 44 1.0682 0.9731 0.0300 0.0401 4
PLX-4720 SKMEL28 0.0100
uM
 24
hr
 1
PLX-4720 SKMEL28 0.0100
uM
 24
hr
 2
PLX-4720 SKMEL28 0.0100
uM
 24
hr
 3
PLX-4720 SKMEL28 0.0100
uM
 24
hr
 4
PLX-4720 SKMEL28 0.0100
uM
 48
hr
 2698 77 1.5611 1.4317 0.0285 0.0306 1
PLX-4720 SKMEL28 0.0100
uM
 48
hr
 2588 83 1.4920 1.4317 0.0321 0.0306 2
PLX-4720 SKMEL28 0.0100
uM
 48
hr
 2231 73 1.2853 1.4317 0.0327 0.0306 3
PLX-4720 SKMEL28 0.0100
uM
 48
hr
 2401 70 1.3884 1.4317 0.0292 0.0306 4
PLX-4720 SKMEL28 0.0100
uM
 72
hr
 1083 47 0.7771 0.8814 0.0434 0.0409 1
PLX-4720 SKMEL28 0.0100
uM
 72
hr
 1141 44 0.8229 0.8814 0.0386 0.0409 2
PLX-4720 SKMEL28 0.0100
uM
 72
hr
 1326 56 0.9527 0.8814 0.0422 0.0409 3
PLX-4720 SKMEL28 0.0100
uM
 72
hr
 1350 53 0.9729 0.8814 0.0393 0.0409 4
PLX-4720 SKMEL28 0.0316
uM
 24
hr
 1
PLX-4720 SKMEL28 0.0316
uM
 24
hr
 2
PLX-4720 SKMEL28 0.0316
uM
 24
hr
 3
PLX-4720 SKMEL28 0.0316
uM
 24
hr
 4
PLX-4720 SKMEL28 0.0316
uM
 48
hr
 2747 100 1.5766 1.4792 0.0364 0.0349 1
PLX-4720 SKMEL28 0.0316
uM
 48
hr
 2904 96 1.6725 1.4792 0.0331 0.0349 2