Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
SB590885 SKMEL28 1.0000
uM
 48
hr
 1608 72 0.9149 0.9058 0.0448 0.0432 1
SB590885 SKMEL28 1.0000
uM
 48
hr
 1652 72 0.9411 0.9058 0.0436 0.0432 2
SB590885 SKMEL28 1.0000
uM
 48
hr
 1446 60 0.8255 0.9058 0.0415 0.0432 3
SB590885 SKMEL28 1.0000
uM
 48
hr
 1652 71 0.9417 0.9058 0.0430 0.0432 4
SB590885 SKMEL28 1.0000
uM
 72
hr
 748 34 0.5356 0.5442 0.0455 0.0381 1
SB590885 SKMEL28 1.0000
uM
 72
hr
 748 22 0.5446 0.5442 0.0294 0.0381 2
SB590885 SKMEL28 1.0000
uM
 72
hr
 766 31 0.5513 0.5442 0.0405 0.0381 3
SB590885 SKMEL28 1.0000
uM
 72
hr
 755 28 0.5453 0.5442 0.0371 0.0381 4
SB590885 SKMEL28 3.1600
uM
 24
hr
 1
SB590885 SKMEL28 3.1600
uM
 24
hr
 2
SB590885 SKMEL28 3.1600
uM
 24
hr
 3
SB590885 SKMEL28 3.1600
uM
 24
hr
 4
SB590885 SKMEL28 3.1600
uM
 48
hr
 1097 44 0.6272 0.6428 0.0401 0.0466 1
SB590885 SKMEL28 3.1600
uM
 48
hr
 1062 60 0.5968 0.6428 0.0565 0.0466 2
SB590885 SKMEL28 3.1600
uM
 48
hr
 1302 61 0.7391 0.6428 0.0469 0.0466 3
SB590885 SKMEL28 3.1600
uM
 48
hr
 1067 46 0.6081 0.6428 0.0431 0.0466 4
SB590885 SKMEL28 3.1600
uM
 72
hr
 673 176 0.3728 0.3728 0.2615 0.2588 1
SB590885 SKMEL28 3.1600
uM
 72
hr
 600 190 0.3076 0.3728 0.3167 0.2588 2
SB590885 SKMEL28 3.1600
uM
 72
hr
 714 158 0.4171 0.3728 0.2213 0.2588 3
SB590885 SKMEL28 3.1600
uM
 72
hr
 687 162 0.3938 0.3728 0.2358 0.2588 4
PLX-4720 SKMEL28 0.0032
uM
 24
hr
 1
PLX-4720 SKMEL28 0.0032
uM
 24
hr
 2
PLX-4720 SKMEL28 0.0032
uM
 24
hr
 3
PLX-4720 SKMEL28 0.0032
uM
 24
hr
 4
PLX-4720 SKMEL28 0.0032
uM
 48
hr
 1334 53 0.7630 0.8243 0.0397 0.0324 1