Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
SB590885 MZ7-mel 3.1600
uM
 24
hr
 1327 49 0.9682 0.8869 0.0369 0.0357 1
SB590885 MZ7-mel 3.1600
uM
 24
hr
 1301 35 0.9591 0.8869 0.0269 0.0357 2
SB590885 MZ7-mel 3.1600
uM
 24
hr
 1122 41 0.8189 0.8869 0.0365 0.0357 3
SB590885 MZ7-mel 3.1600
uM
 24
hr
 1105 47 0.8015 0.8869 0.0425 0.0357 4
SB590885 MZ7-mel 3.1600
uM
 48
hr
 1791 108 0.5211 0.5450 0.0603 0.0728 1
SB590885 MZ7-mel 3.1600
uM
 48
hr
 2017 159 0.5752 0.5450 0.0788 0.0728 2
SB590885 MZ7-mel 3.1600
uM
 48
hr
 1875 171 0.5276 0.5450 0.0912 0.0728 3
SB590885 MZ7-mel 3.1600
uM
 48
hr
 1912 116 0.5560 0.5450 0.0607 0.0728 4
SB590885 MZ7-mel 3.1600
uM
 72
hr
 1019 155 0.3599 0.3870 0.1521 0.1433 1
SB590885 MZ7-mel 3.1600
uM
 72
hr
 939 140 0.3328 0.3870 0.1491 0.1433 2
SB590885 MZ7-mel 3.1600
uM
 72
hr
 1179 161 0.4241 0.3870 0.1366 0.1433 3
SB590885 MZ7-mel 3.1600
uM
 72
hr
 1197 162 0.4311 0.3870 0.1353 0.1433 4
PLX-4720 MZ7-mel 0.0032
uM
 24
hr
 1396 15 1.0462 1.0184 0.0107 0.0130 1
PLX-4720 MZ7-mel 0.0032
uM
 24
hr
 1447 14 1.0856 1.0184 0.0097 0.0130 2
PLX-4720 MZ7-mel 0.0032
uM
 24
hr
 1331 23 0.9909 1.0184 0.0173 0.0130 3
PLX-4720 MZ7-mel 0.0032
uM
 24
hr
 1273 18 0.9508 1.0184 0.0141 0.0130 4
PLX-4720 MZ7-mel 0.0032
uM
 48
hr
 3264 45 0.9966 1.0423 0.0138 0.0158 1
PLX-4720 MZ7-mel 0.0032
uM
 48
hr
 3180 54 0.9678 1.0423 0.0170 0.0158 2
PLX-4720 MZ7-mel 0.0032
uM
 48
hr
 3636 55 1.1087 1.0423 0.0151 0.0158 3
PLX-4720 MZ7-mel 0.0032
uM
 48
hr
 3603 62 1.0963 1.0423 0.0172 0.0158 4
PLX-4720 MZ7-mel 0.0032
uM
 72
hr
 3641 39 1.5004 1.2790 0.0107 0.0184 1
PLX-4720 MZ7-mel 0.0032
uM
 72
hr
 3166 52 1.2971 1.2790 0.0164 0.0184 2
PLX-4720 MZ7-mel 0.0032
uM
 72
hr
 3209 78 1.3042 1.2790 0.0243 0.0184 3
PLX-4720 MZ7-mel 0.0032
uM
 72
hr
 2490 55 1.0143 1.2790 0.0221 0.0184 4
PLX-4720 MZ7-mel 0.0100
uM
 24
hr
 1498 19 1.1205 1.0212 0.0127 0.0082 1