Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
PLX-4720 MMAC-SF 0.1000
uM
 48
hr
 3725 161 0.9396 1.0083 0.0432 0.0443 3
PLX-4720 MMAC-SF 0.1000
uM
 48
hr
 4
PLX-4720 MMAC-SF 0.1000
uM
 72
hr
 2233 64 0.6310 0.6321 0.0287 0.0346 1
PLX-4720 MMAC-SF 0.1000
uM
 72
hr
 2310 81 0.6484 0.6321 0.0351 0.0346 2
PLX-4720 MMAC-SF 0.1000
uM
 72
hr
 2203 90 0.6147 0.6321 0.0409 0.0346 3
PLX-4720 MMAC-SF 0.1000
uM
 72
hr
 2256 76 0.6342 0.6321 0.0337 0.0346 4
PLX-4720 MMAC-SF 0.3160
uM
 24
hr
 1
PLX-4720 MMAC-SF 0.3160
uM
 24
hr
 2
PLX-4720 MMAC-SF 0.3160
uM
 24
hr
 2636 92 0.9891 0.9910 0.0349 0.0417 3
PLX-4720 MMAC-SF 0.3160
uM
 24
hr
 2684 130 0.9930 0.9910 0.0484 0.0417 4
PLX-4720 MMAC-SF 0.3160
uM
 48
hr
 3675 163 0.9259 0.8542 0.0444 0.0469 1
PLX-4720 MMAC-SF 0.3160
uM
 48
hr
 2
PLX-4720 MMAC-SF 0.3160
uM
 48
hr
 3346 150 0.8425 0.8542 0.0448 0.0469 3
PLX-4720 MMAC-SF 0.3160
uM
 48
hr
 3177 164 0.7943 0.8542 0.0516 0.0469 4
PLX-4720 MMAC-SF 0.3160
uM
 72
hr
 1868 110 0.5114 0.5313 0.0589 0.0549 1
PLX-4720 MMAC-SF 0.3160
uM
 72
hr
 1848 102 0.5079 0.5313 0.0552 0.0549 2
PLX-4720 MMAC-SF 0.3160
uM
 72
hr
 2041 115 0.5603 0.5313 0.0563 0.0549 3
PLX-4720 MMAC-SF 0.3160
uM
 72
hr
 1972 97 0.5455 0.5313 0.0492 0.0549 4
PLX-4720 MMAC-SF 1.0000
uM
 24
hr
 1
PLX-4720 MMAC-SF 1.0000
uM
 24
hr
 2
PLX-4720 MMAC-SF 1.0000
uM
 24
hr
 2799 136 1.0353 1.0153 0.0486 0.0492 3
PLX-4720 MMAC-SF 1.0000
uM
 24
hr
 2694 134 0.9953 1.0153 0.0497 0.0492 4
PLX-4720 MMAC-SF 1.0000
uM
 48
hr
 3165 187 0.7851 0.7644 0.0591 0.0555 1
PLX-4720 MMAC-SF 1.0000
uM
 48
hr
 3215 174 0.8017 0.7644 0.0541 0.0555 2
PLX-4720 MMAC-SF 1.0000
uM
 48
hr
 2899 158 0.7226 0.7644 0.0545 0.0555 3