Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | WM1552C | 0.0316 | uM | 24 | hr | 2747 | 161 | 1.0321 | 1.0309 | 0.0586 | 0.0522 | 2 |
| PLX-4720 | WM1552C | 0.0316 | uM | 24 | hr | 3 | ||||||
| PLX-4720 | WM1552C | 0.0316 | uM | 24 | hr | 4 | ||||||
| PLX-4720 | WM1552C | 0.0316 | uM | 48 | hr | 3494 | 184 | 1.0529 | 1.0128 | 0.0527 | 0.0655 | 1 |
| PLX-4720 | WM1552C | 0.0316 | uM | 48 | hr | 3579 | 199 | 1.0752 | 1.0128 | 0.0556 | 0.0655 | 2 |
| PLX-4720 | WM1552C | 0.0316 | uM | 48 | hr | 3198 | 279 | 0.9285 | 1.0128 | 0.0872 | 0.0655 | 3 |
| PLX-4720 | WM1552C | 0.0316 | uM | 48 | hr | 3348 | 222 | 0.9944 | 1.0128 | 0.0663 | 0.0655 | 4 |
| PLX-4720 | WM1552C | 0.0316 | uM | 72 | hr | 7134 | 476 | 1.2914 | 1.1291 | 0.0667 | 0.0682 | 1 |
| PLX-4720 | WM1552C | 0.0316 | uM | 72 | hr | 6749 | 450 | 1.2218 | 1.1291 | 0.0667 | 0.0682 | 2 |
| PLX-4720 | WM1552C | 0.0316 | uM | 72 | hr | 5580 | 370 | 1.0105 | 1.1291 | 0.0663 | 0.0682 | 3 |
| PLX-4720 | WM1552C | 0.0316 | uM | 72 | hr | 5522 | 404 | 0.9927 | 1.1291 | 0.0732 | 0.0682 | 4 |
| PLX-4720 | WM1552C | 0.1000 | uM | 24 | hr | 2880 | 185 | 1.0756 | 1.0830 | 0.0642 | 0.0708 | 1 |
| PLX-4720 | WM1552C | 0.1000 | uM | 24 | hr | 2961 | 229 | 1.0904 | 1.0830 | 0.0773 | 0.0708 | 2 |
| PLX-4720 | WM1552C | 0.1000 | uM | 24 | hr | 3 | ||||||
| PLX-4720 | WM1552C | 0.1000 | uM | 24 | hr | 4 | ||||||
| PLX-4720 | WM1552C | 0.1000 | uM | 48 | hr | 3261 | 132 | 0.9953 | 0.9768 | 0.0405 | 0.0534 | 1 |
| PLX-4720 | WM1552C | 0.1000 | uM | 48 | hr | 3240 | 178 | 0.9740 | 0.9768 | 0.0549 | 0.0534 | 2 |
| PLX-4720 | WM1552C | 0.1000 | uM | 48 | hr | 3217 | 189 | 0.9632 | 0.9768 | 0.0588 | 0.0534 | 3 |
| PLX-4720 | WM1552C | 0.1000 | uM | 48 | hr | 3258 | 194 | 0.9747 | 0.9768 | 0.0595 | 0.0534 | 4 |
| PLX-4720 | WM1552C | 0.1000 | uM | 72 | hr | 6333 | 408 | 1.1492 | 1.0334 | 0.0644 | 0.0630 | 1 |
| PLX-4720 | WM1552C | 0.1000 | uM | 72 | hr | 6428 | 385 | 1.1721 | 1.0334 | 0.0599 | 0.0630 | 2 |
| PLX-4720 | WM1552C | 0.1000 | uM | 72 | hr | 5011 | 320 | 0.9099 | 1.0334 | 0.0639 | 0.0630 | 3 |
| PLX-4720 | WM1552C | 0.1000 | uM | 72 | hr | 4971 | 318 | 0.9025 | 1.0334 | 0.0640 | 0.0630 | 4 |
| PLX-4720 | WM1552C | 0.3160 | uM | 24 | hr | 2679 | 166 | 1.0030 | 1.0175 | 0.0620 | 0.0728 | 1 |
| PLX-4720 | WM1552C | 0.3160 | uM | 24 | hr | 2822 | 236 | 1.0321 | 1.0175 | 0.0836 | 0.0728 | 2 |