Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
PLX-4720 K2 0.3160
uM
 72
hr
 4
PLX-4720 K2 1.0000
uM
 24
hr
 1778 60 1.0104 0.6205 0.0337 0.0503 1
PLX-4720 K2 1.0000
uM
 24
hr
 1374 60 0.7728 0.6205 0.0437 0.0503 2
PLX-4720 K2 1.0000
uM
 24
hr
 696 51 0.3793 0.6205 0.0733 0.0503 3
PLX-4720 K2 1.0000
uM
 24
hr
 572 29 0.3194 0.6205 0.0507 0.0503 4
PLX-4720 K2 1.0000
uM
 48
hr
 1851 135 0.6262 0.4204 0.0729 0.0858 1
PLX-4720 K2 1.0000
uM
 48
hr
 1663 122 0.5624 0.4204 0.0734 0.0858 2
PLX-4720 K2 1.0000
uM
 48
hr
 776 83 0.2529 0.4204 0.1070 0.0858 3
PLX-4720 K2 1.0000
uM
 48
hr
 723 65 0.2401 0.4204 0.0899 0.0858 4
PLX-4720 K2 1.0000
uM
 72
hr
 1
PLX-4720 K2 1.0000
uM
 72
hr
 2
PLX-4720 K2 1.0000
uM
 72
hr
 3
PLX-4720 K2 1.0000
uM
 72
hr
 4
PLX-4720 K2 3.1600
uM
 24
hr
 1943 256 0.9922 0.5937 0.1318 0.1531 1
PLX-4720 K2 3.1600
uM
 24
hr
 1556 269 0.7569 0.5937 0.1729 0.1531 2
PLX-4720 K2 3.1600
uM
 24
hr
 667 92 0.3382 0.5937 0.1379 0.1531 3
PLX-4720 K2 3.1600
uM
 24
hr
 589 100 0.2876 0.5937 0.1698 0.1531 4
PLX-4720 K2 3.1600
uM
 48
hr
 2193 334 0.6784 0.4397 0.1523 0.1731 1
PLX-4720 K2 3.1600
uM
 48
hr
 1945 314 0.5952 0.4397 0.1614 0.1731 2
PLX-4720 K2 3.1600
uM
 48
hr
 784 142 0.2343 0.4397 0.1811 0.1731 3
PLX-4720 K2 3.1600
uM
 48
hr
 856 169 0.2507 0.4397 0.1974 0.1731 4
PLX-4720 K2 3.1600
uM
 72
hr
 1
PLX-4720 K2 3.1600
uM
 72
hr
 2
PLX-4720 K2 3.1600
uM
 72
hr
 3
PLX-4720 K2 3.1600
uM
 72
hr
 4