Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
PLX-4720 K2 0.0316
uM
 72
hr
 3
PLX-4720 K2 0.0316
uM
 72
hr
 4
PLX-4720 K2 0.1000
uM
 24
hr
 3925 13 2.3008 1.4881 0.0033 0.0032 1
PLX-4720 K2 0.1000
uM
 24
hr
 3247 10 1.9038 1.4881 0.0031 0.0032 2
PLX-4720 K2 0.1000
uM
 24
hr
 1780 7 1.0427 1.4881 0.0039 0.0032 3
PLX-4720 K2 0.1000
uM
 24
hr
 1202 3 0.7052 1.4881 0.0025 0.0032 4
PLX-4720 K2 0.1000
uM
 48
hr
 2266 5 0.8251 0.8459 0.0022 0.0053 1
PLX-4720 K2 0.1000
uM
 48
hr
 2517 11 0.9146 0.8459 0.0044 0.0053 2
PLX-4720 K2 0.1000
uM
 48
hr
 2612 16 0.9474 0.8459 0.0061 0.0053 3
PLX-4720 K2 0.1000
uM
 48
hr
 1925 16 0.6967 0.8459 0.0083 0.0053 4
PLX-4720 K2 0.1000
uM
 72
hr
 1
PLX-4720 K2 0.1000
uM
 72
hr
 2
PLX-4720 K2 0.1000
uM
 72
hr
 3
PLX-4720 K2 0.1000
uM
 72
hr
 4
PLX-4720 K2 0.3160
uM
 24
hr
 2657 8 1.5579 0.9548 0.0030 0.0082 1
PLX-4720 K2 0.3160
uM
 24
hr
 1872 9 1.0957 0.9548 0.0048 0.0082 2
PLX-4720 K2 0.3160
uM
 24
hr
 1345 11 0.7846 0.9548 0.0082 0.0082 3
PLX-4720 K2 0.3160
uM
 24
hr
 659 11 0.3811 0.9548 0.0167 0.0082 4
PLX-4720 K2 0.3160
uM
 48
hr
 2684 38 0.9656 0.6270 0.0142 0.0166 1
PLX-4720 K2 0.3160
uM
 48
hr
 1880 20 0.6788 0.6270 0.0106 0.0166 2
PLX-4720 K2 0.3160
uM
 48
hr
 1504 23 0.5405 0.6270 0.0153 0.0166 3
PLX-4720 K2 0.3160
uM
 48
hr
 909 24 0.3230 0.6270 0.0264 0.0166 4
PLX-4720 K2 0.3160
uM
 72
hr
 1
PLX-4720 K2 0.3160
uM
 72
hr
 2
PLX-4720 K2 0.3160
uM
 72
hr
 3