Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
PLX-4720 MZ7-mel 1.0000
uM
 24
hr
 1048 14 0.7833 0.9557 0.0134 0.0127 4
PLX-4720 MZ7-mel 1.0000
uM
 48
hr
 2344 64 0.7059 0.6084 0.0273 0.0277 1
PLX-4720 MZ7-mel 1.0000
uM
 48
hr
 2028 48 0.6130 0.6084 0.0237 0.0277 2
PLX-4720 MZ7-mel 1.0000
uM
 48
hr
 1851 43 0.5598 0.6084 0.0232 0.0277 3
PLX-4720 MZ7-mel 1.0000
uM
 48
hr
 1861 68 0.5551 0.6084 0.0365 0.0277 4
PLX-4720 MZ7-mel 1.0000
uM
 72
hr
 916 82 0.3474 0.3821 0.0895 0.1052 1
PLX-4720 MZ7-mel 1.0000
uM
 72
hr
 841 130 0.2962 0.3821 0.1546 0.1052 2
PLX-4720 MZ7-mel 1.0000
uM
 72
hr
 1358 121 0.5153 0.3821 0.0891 0.1052 3
PLX-4720 MZ7-mel 1.0000
uM
 72
hr
 972 85 0.3695 0.3821 0.0874 0.1052 4
PLX-4720 MZ7-mel 3.1600
uM
 24
hr
 1193 44 0.8705 0.7951 0.0369 0.0325 1
PLX-4720 MZ7-mel 3.1600
uM
 24
hr
 1193 28 0.8826 0.7951 0.0235 0.0325 2
PLX-4720 MZ7-mel 3.1600
uM
 24
hr
 857 36 0.6220 0.7951 0.0420 0.0325 3
PLX-4720 MZ7-mel 3.1600
uM
 24
hr
 1093 30 0.8053 0.7951 0.0274 0.0325 4
PLX-4720 MZ7-mel 3.1600
uM
 48
hr
 1655 70 0.4907 0.4803 0.0423 0.0483 1
PLX-4720 MZ7-mel 3.1600
uM
 48
hr
 1663 69 0.4935 0.4803 0.0415 0.0483 2
PLX-4720 MZ7-mel 3.1600
uM
 48
hr
 1612 84 0.4731 0.4803 0.0521 0.0483 3
PLX-4720 MZ7-mel 3.1600
uM
 48
hr
 1589 91 0.4638 0.4803 0.0573 0.0483 4
PLX-4720 MZ7-mel 3.1600
uM
 72
hr
 977 184 0.3303 0.3290 0.1883 0.1506 1
PLX-4720 MZ7-mel 3.1600
uM
 72
hr
 721 72 0.2703 0.3290 0.0999 0.1506 2
PLX-4720 MZ7-mel 3.1600
uM
 72
hr
 1016 159 0.3570 0.3290 0.1565 0.1506 3
PLX-4720 MZ7-mel 3.1600
uM
 72
hr
 1021 161 0.3582 0.3290 0.1577 0.1506 4
AZ-628 MZ7-mel 0.0032
uM
 24
hr
 1402 13 1.0523 1.0250 0.0093 0.0132 1
AZ-628 MZ7-mel 0.0032
uM
 24
hr
 1453 25 1.0818 1.0250 0.0172 0.0132 2
AZ-628 MZ7-mel 0.0032
uM
 24
hr
 1288 9 0.9689 1.0250 0.0070 0.0132 3
AZ-628 MZ7-mel 0.0032
uM
 24
hr
 1342 26 0.9970 1.0250 0.0194 0.0132 4