Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | MZ7-mel | 0.1000 | uM | 24 | hr | 1560 | 9 | 1.1750 | 1.1936 | 0.0058 | 0.0050 | 3 |
| PLX-4720 | MZ7-mel | 0.1000 | uM | 24 | hr | 1449 | 12 | 1.0886 | 1.1936 | 0.0083 | 0.0050 | 4 |
| PLX-4720 | MZ7-mel | 0.1000 | uM | 48 | hr | 3655 | 25 | 1.1238 | 1.0946 | 0.0068 | 0.0113 | 1 |
| PLX-4720 | MZ7-mel | 0.1000 | uM | 48 | hr | 3445 | 36 | 1.0554 | 1.0946 | 0.0105 | 0.0113 | 2 |
| PLX-4720 | MZ7-mel | 0.1000 | uM | 48 | hr | 3510 | 48 | 1.0718 | 1.0946 | 0.0137 | 0.0113 | 3 |
| PLX-4720 | MZ7-mel | 0.1000 | uM | 48 | hr | 3694 | 53 | 1.1272 | 1.0946 | 0.0143 | 0.0113 | 4 |
| PLX-4720 | MZ7-mel | 0.1000 | uM | 72 | hr | 1562 | 24 | 0.6407 | 0.6612 | 0.0154 | 0.0198 | 1 |
| PLX-4720 | MZ7-mel | 0.1000 | uM | 72 | hr | 1535 | 30 | 0.6269 | 0.6612 | 0.0195 | 0.0198 | 2 |
| PLX-4720 | MZ7-mel | 0.1000 | uM | 72 | hr | 1734 | 38 | 0.7065 | 0.6612 | 0.0219 | 0.0198 | 3 |
| PLX-4720 | MZ7-mel | 0.1000 | uM | 72 | hr | 1647 | 37 | 0.6707 | 0.6612 | 0.0225 | 0.0198 | 4 |
| PLX-4720 | MZ7-mel | 0.3160 | uM | 24 | hr | 1607 | 21 | 1.2015 | 1.1278 | 0.0131 | 0.0092 | 1 |
| PLX-4720 | MZ7-mel | 0.3160 | uM | 24 | hr | 1604 | 15 | 1.2038 | 1.1278 | 0.0094 | 0.0092 | 2 |
| PLX-4720 | MZ7-mel | 0.3160 | uM | 24 | hr | 1411 | 8 | 1.0629 | 1.1278 | 0.0057 | 0.0092 | 3 |
| PLX-4720 | MZ7-mel | 0.3160 | uM | 24 | hr | 1389 | 12 | 1.0432 | 1.1278 | 0.0086 | 0.0092 | 4 |
| PLX-4720 | MZ7-mel | 0.3160 | uM | 48 | hr | 2900 | 79 | 0.8734 | 0.9313 | 0.0272 | 0.0205 | 1 |
| PLX-4720 | MZ7-mel | 0.3160 | uM | 48 | hr | 3026 | 56 | 0.9195 | 0.9313 | 0.0185 | 0.0205 | 2 |
| PLX-4720 | MZ7-mel | 0.3160 | uM | 48 | hr | 3327 | 51 | 1.0142 | 0.9313 | 0.0153 | 0.0205 | 3 |
| PLX-4720 | MZ7-mel | 0.3160 | uM | 48 | hr | 3028 | 63 | 0.9180 | 0.9313 | 0.0208 | 0.0205 | 4 |
| PLX-4720 | MZ7-mel | 0.3160 | uM | 72 | hr | 1286 | 57 | 0.5119 | 0.5036 | 0.0443 | 0.0439 | 1 |
| PLX-4720 | MZ7-mel | 0.3160 | uM | 72 | hr | 1013 | 53 | 0.3999 | 0.5036 | 0.0523 | 0.0439 | 2 |
| PLX-4720 | MZ7-mel | 0.3160 | uM | 72 | hr | 1616 | 51 | 0.6519 | 0.5036 | 0.0316 | 0.0439 | 3 |
| PLX-4720 | MZ7-mel | 0.3160 | uM | 72 | hr | 1136 | 54 | 0.4507 | 0.5036 | 0.0475 | 0.0439 | 4 |
| PLX-4720 | MZ7-mel | 1.0000 | uM | 24 | hr | 1474 | 25 | 1.0977 | 0.9557 | 0.0170 | 0.0127 | 1 |
| PLX-4720 | MZ7-mel | 1.0000 | uM | 24 | hr | 1631 | 28 | 1.2144 | 0.9557 | 0.0172 | 0.0127 | 2 |
| PLX-4720 | MZ7-mel | 1.0000 | uM | 24 | hr | 963 | 3 | 0.7273 | 0.9557 | 0.0031 | 0.0127 | 3 |