Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | MMAC-SF | 0.0100 | uM | 48 | hr | 3631 | 162 | 0.9145 | 1.0245 | 0.0446 | 0.0457 | 2 |
| PLX-4720 | MMAC-SF | 0.0100 | uM | 48 | hr | 4227 | 204 | 1.0606 | 1.0245 | 0.0483 | 0.0457 | 3 |
| PLX-4720 | MMAC-SF | 0.0100 | uM | 48 | hr | 3997 | 185 | 1.0049 | 1.0245 | 0.0463 | 0.0457 | 4 |
| PLX-4720 | MMAC-SF | 0.0100 | uM | 72 | hr | 3415 | 132 | 0.9551 | 0.9229 | 0.0387 | 0.0424 | 1 |
| PLX-4720 | MMAC-SF | 0.0100 | uM | 72 | hr | 3337 | 141 | 0.9298 | 0.9229 | 0.0423 | 0.0424 | 2 |
| PLX-4720 | MMAC-SF | 0.0100 | uM | 72 | hr | 3247 | 138 | 0.9044 | 0.9229 | 0.0425 | 0.0424 | 3 |
| PLX-4720 | MMAC-SF | 0.0100 | uM | 72 | hr | 3252 | 150 | 0.9024 | 0.9229 | 0.0461 | 0.0424 | 4 |
| PLX-4720 | MMAC-SF | 0.0316 | uM | 24 | hr | 1 | ||||||
| PLX-4720 | MMAC-SF | 0.0316 | uM | 24 | hr | 2 | ||||||
| PLX-4720 | MMAC-SF | 0.0316 | uM | 24 | hr | 2811 | 104 | 1.0524 | 0.9743 | 0.0370 | 0.0397 | 3 |
| PLX-4720 | MMAC-SF | 0.0316 | uM | 24 | hr | 2407 | 102 | 0.8962 | 0.9743 | 0.0424 | 0.0397 | 4 |
| PLX-4720 | MMAC-SF | 0.0316 | uM | 48 | hr | 4087 | 164 | 1.0342 | 1.0082 | 0.0401 | 0.0434 | 1 |
| PLX-4720 | MMAC-SF | 0.0316 | uM | 48 | hr | 3927 | 159 | 0.9933 | 1.0082 | 0.0405 | 0.0434 | 2 |
| PLX-4720 | MMAC-SF | 0.0316 | uM | 48 | hr | 4078 | 195 | 1.0237 | 1.0082 | 0.0478 | 0.0434 | 3 |
| PLX-4720 | MMAC-SF | 0.0316 | uM | 48 | hr | 3899 | 176 | 0.9815 | 1.0082 | 0.0451 | 0.0434 | 4 |
| PLX-4720 | MMAC-SF | 0.0316 | uM | 72 | hr | 3137 | 142 | 0.8713 | 0.8603 | 0.0453 | 0.0386 | 1 |
| PLX-4720 | MMAC-SF | 0.0316 | uM | 72 | hr | 2961 | 101 | 0.8320 | 0.8603 | 0.0341 | 0.0386 | 2 |
| PLX-4720 | MMAC-SF | 0.0316 | uM | 72 | hr | 3054 | 104 | 0.8582 | 0.8603 | 0.0341 | 0.0386 | 3 |
| PLX-4720 | MMAC-SF | 0.0316 | uM | 72 | hr | 3153 | 129 | 0.8797 | 0.8603 | 0.0409 | 0.0386 | 4 |
| PLX-4720 | MMAC-SF | 0.1000 | uM | 24 | hr | 1 | ||||||
| PLX-4720 | MMAC-SF | 0.1000 | uM | 24 | hr | 2 | ||||||
| PLX-4720 | MMAC-SF | 0.1000 | uM | 24 | hr | 2915 | 121 | 1.0863 | 1.0375 | 0.0415 | 0.0422 | 3 |
| PLX-4720 | MMAC-SF | 0.1000 | uM | 24 | hr | 2657 | 114 | 0.9887 | 1.0375 | 0.0429 | 0.0422 | 4 |
| PLX-4720 | MMAC-SF | 0.1000 | uM | 48 | hr | 4127 | 163 | 1.0450 | 1.0083 | 0.0395 | 0.0443 | 1 |
| PLX-4720 | MMAC-SF | 0.1000 | uM | 48 | hr | 4154 | 208 | 1.0403 | 1.0083 | 0.0501 | 0.0443 | 2 |