Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB590885 | MMAC-SF | 3.1600 | uM | 48 | hr | 3045 | 335 | 0.7144 | 0.6841 | 0.1100 | 0.0951 | 1 |
| SB590885 | MMAC-SF | 3.1600 | uM | 48 | hr | 2928 | 285 | 0.6968 | 0.6841 | 0.0973 | 0.0951 | 2 |
| SB590885 | MMAC-SF | 3.1600 | uM | 48 | hr | 2796 | 237 | 0.6746 | 0.6841 | 0.0848 | 0.0951 | 3 |
| SB590885 | MMAC-SF | 3.1600 | uM | 48 | hr | 2707 | 239 | 0.6506 | 0.6841 | 0.0883 | 0.0951 | 4 |
| SB590885 | MMAC-SF | 3.1600 | uM | 72 | hr | 1476 | 367 | 0.3226 | 0.3415 | 0.2486 | 0.2237 | 1 |
| SB590885 | MMAC-SF | 3.1600 | uM | 72 | hr | 1533 | 351 | 0.3439 | 0.3415 | 0.2290 | 0.2237 | 2 |
| SB590885 | MMAC-SF | 3.1600 | uM | 72 | hr | 1512 | 309 | 0.3500 | 0.3415 | 0.2044 | 0.2237 | 3 |
| SB590885 | MMAC-SF | 3.1600 | uM | 72 | hr | 1526 | 325 | 0.3494 | 0.3415 | 0.2130 | 0.2237 | 4 |
| PLX-4720 | MMAC-SF | 0.0032 | uM | 24 | hr | 1 | ||||||
| PLX-4720 | MMAC-SF | 0.0032 | uM | 24 | hr | 2 | ||||||
| PLX-4720 | MMAC-SF | 0.0032 | uM | 24 | hr | 2591 | 106 | 0.9661 | 1.0192 | 0.0409 | 0.0449 | 3 |
| PLX-4720 | MMAC-SF | 0.0032 | uM | 24 | hr | 2900 | 142 | 1.0723 | 1.0192 | 0.0490 | 0.0449 | 4 |
| PLX-4720 | MMAC-SF | 0.0032 | uM | 48 | hr | 3725 | 177 | 0.9353 | 0.9201 | 0.0475 | 0.0462 | 1 |
| PLX-4720 | MMAC-SF | 0.0032 | uM | 48 | hr | 3237 | 153 | 0.8130 | 0.9201 | 0.0473 | 0.0462 | 2 |
| PLX-4720 | MMAC-SF | 0.0032 | uM | 48 | hr | 3875 | 178 | 0.9746 | 0.9201 | 0.0459 | 0.0462 | 3 |
| PLX-4720 | MMAC-SF | 0.0032 | uM | 48 | hr | 3799 | 168 | 0.9572 | 0.9201 | 0.0442 | 0.0462 | 4 |
| PLX-4720 | MMAC-SF | 0.0032 | uM | 72 | hr | 3068 | 127 | 0.8556 | 0.9368 | 0.0414 | 0.0394 | 1 |
| PLX-4720 | MMAC-SF | 0.0032 | uM | 72 | hr | 3236 | 119 | 0.9068 | 0.9368 | 0.0368 | 0.0394 | 2 |
| PLX-4720 | MMAC-SF | 0.0032 | uM | 72 | hr | 3534 | 139 | 0.9877 | 0.9368 | 0.0393 | 0.0394 | 3 |
| PLX-4720 | MMAC-SF | 0.0032 | uM | 72 | hr | 3571 | 143 | 0.9973 | 0.9368 | 0.0400 | 0.0394 | 4 |
| PLX-4720 | MMAC-SF | 0.0100 | uM | 24 | hr | 1 | ||||||
| PLX-4720 | MMAC-SF | 0.0100 | uM | 24 | hr | 2 | ||||||
| PLX-4720 | MMAC-SF | 0.0100 | uM | 24 | hr | 2545 | 114 | 0.9451 | 0.9436 | 0.0448 | 0.0443 | 3 |
| PLX-4720 | MMAC-SF | 0.0100 | uM | 24 | hr | 2534 | 111 | 0.9420 | 0.9436 | 0.0438 | 0.0443 | 4 |
| PLX-4720 | MMAC-SF | 0.0100 | uM | 48 | hr | 4435 | 194 | 1.1180 | 1.0245 | 0.0437 | 0.0457 | 1 |