Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | LOXIMVI | 1.0000 | uM | 72 | hr | 3408 | 1.9395 | 1.7824 | 0.0552 | 0.0542 | 4 | |
| PLX-4720 | LOXIMVI | 3.1600 | uM | 24 | hr | 2476 | 63 | 0.9854 | 0.9127 | 0.0254 | 0.0445 | 1 |
| PLX-4720 | LOXIMVI | 3.1600 | uM | 24 | hr | 2830 | 169 | 1.0866 | 0.9127 | 0.0597 | 0.0445 | 2 |
| PLX-4720 | LOXIMVI | 3.1600 | uM | 24 | hr | 2002 | 87 | 0.7820 | 0.9127 | 0.0435 | 0.0445 | 3 |
| PLX-4720 | LOXIMVI | 3.1600 | uM | 24 | hr | 2052 | 101 | 0.7967 | 0.9127 | 0.0492 | 0.0445 | 4 |
| PLX-4720 | LOXIMVI | 3.1600 | uM | 48 | hr | 1621 | 0.9648 | 0.9895 | 0.1147 | 0.1134 | 1 | |
| PLX-4720 | LOXIMVI | 3.1600 | uM | 48 | hr | 1726 | 1.0206 | 0.9895 | 0.1205 | 0.1134 | 2 | |
| PLX-4720 | LOXIMVI | 3.1600 | uM | 48 | hr | 1595 | 0.9614 | 0.9895 | 0.1035 | 0.1134 | 3 | |
| PLX-4720 | LOXIMVI | 3.1600 | uM | 48 | hr | 1699 | 1.0112 | 0.9895 | 0.1148 | 0.1134 | 4 | |
| PLX-4720 | LOXIMVI | 3.1600 | uM | 72 | hr | 2035 | 1.0938 | 0.9994 | 0.1076 | 0.1595 | 1 | |
| PLX-4720 | LOXIMVI | 3.1600 | uM | 72 | hr | 1730 | 0.8794 | 0.9994 | 0.1561 | 0.1595 | 2 | |
| PLX-4720 | LOXIMVI | 3.1600 | uM | 72 | hr | 1420 | 0.6168 | 0.9994 | 0.2789 | 0.1595 | 3 | |
| PLX-4720 | LOXIMVI | 3.1600 | uM | 72 | hr | 2583 | 1.4076 | 0.9994 | 0.0952 | 0.1595 | 4 | |
| AZ-628 | LOXIMVI | 0.0032 | uM | 24 | hr | 2745 | 179 | 1.0479 | 0.9629 | 0.0652 | 0.0535 | 1 |
| AZ-628 | LOXIMVI | 0.0032 | uM | 24 | hr | 2792 | 158 | 1.0756 | 0.9629 | 0.0566 | 0.0535 | 2 |
| AZ-628 | LOXIMVI | 0.0032 | uM | 24 | hr | 2230 | 92 | 0.8731 | 0.9629 | 0.0413 | 0.0535 | 3 |
| AZ-628 | LOXIMVI | 0.0032 | uM | 24 | hr | 2206 | 112 | 0.8551 | 0.9629 | 0.0508 | 0.0535 | 4 |
| AZ-628 | LOXIMVI | 0.0032 | uM | 48 | hr | 1572 | 0.9648 | 1.0619 | 0.0872 | 0.0814 | 1 | |
| AZ-628 | LOXIMVI | 0.0032 | uM | 48 | hr | 1759 | 1.0858 | 1.0619 | 0.0819 | 0.0814 | 2 | |
| AZ-628 | LOXIMVI | 0.0032 | uM | 48 | hr | 1968 | 1.2364 | 1.0619 | 0.0655 | 0.0814 | 3 | |
| AZ-628 | LOXIMVI | 0.0032 | uM | 48 | hr | 1572 | 0.9607 | 1.0619 | 0.0910 | 0.0814 | 4 | |
| AZ-628 | LOXIMVI | 0.0032 | uM | 72 | hr | 2824 | 1.4395 | 1.7663 | 0.1537 | 0.1389 | 1 | |
| AZ-628 | LOXIMVI | 0.0032 | uM | 72 | hr | 2930 | 1.4950 | 1.7663 | 0.1529 | 0.1389 | 2 | |
| AZ-628 | LOXIMVI | 0.0032 | uM | 72 | hr | 4086 | 2.1732 | 1.7663 | 0.1170 | 0.1389 | 3 | |
| AZ-628 | LOXIMVI | 0.0032 | uM | 72 | hr | 3744 | 1.9575 | 1.7663 | 0.1319 | 0.1389 | 4 |