Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | LOXIMVI | 0.1000 | uM | 72 | hr | 4496 | 2.5954 | 2.4826 | 0.0416 | 0.0395 | 3 | |
| PLX-4720 | LOXIMVI | 0.1000 | uM | 72 | hr | 4643 | 2.7026 | 2.4826 | 0.0336 | 0.0395 | 4 | |
| PLX-4720 | LOXIMVI | 0.3160 | uM | 24 | hr | 2760 | 70 | 1.0985 | 1.0470 | 0.0254 | 0.0330 | 1 |
| PLX-4720 | LOXIMVI | 0.3160 | uM | 24 | hr | 2946 | 112 | 1.1573 | 1.0470 | 0.0380 | 0.0330 | 2 |
| PLX-4720 | LOXIMVI | 0.3160 | uM | 24 | hr | 2359 | 71 | 0.9343 | 1.0470 | 0.0301 | 0.0330 | 3 |
| PLX-4720 | LOXIMVI | 0.3160 | uM | 24 | hr | 2542 | 98 | 0.9980 | 1.0470 | 0.0386 | 0.0330 | 4 |
| PLX-4720 | LOXIMVI | 0.3160 | uM | 48 | hr | 2792 | 1.8065 | 1.6660 | 0.0376 | 0.0482 | 1 | |
| PLX-4720 | LOXIMVI | 0.3160 | uM | 48 | hr | 2390 | 1.5120 | 1.6660 | 0.0590 | 0.0482 | 2 | |
| PLX-4720 | LOXIMVI | 0.3160 | uM | 48 | hr | 2782 | 1.7870 | 1.6660 | 0.0446 | 0.0482 | 3 | |
| PLX-4720 | LOXIMVI | 0.3160 | uM | 48 | hr | 2444 | 1.5584 | 1.6660 | 0.0516 | 0.0482 | 4 | |
| PLX-4720 | LOXIMVI | 0.3160 | uM | 72 | hr | 4214 | 2.4316 | 2.2146 | 0.0420 | 0.0480 | 1 | |
| PLX-4720 | LOXIMVI | 0.3160 | uM | 72 | hr | 3712 | 2.1382 | 2.2146 | 0.0436 | 0.0480 | 2 | |
| PLX-4720 | LOXIMVI | 0.3160 | uM | 72 | hr | 3751 | 2.1262 | 2.2146 | 0.0589 | 0.0480 | 3 | |
| PLX-4720 | LOXIMVI | 0.3160 | uM | 72 | hr | 3769 | 2.1623 | 2.2146 | 0.0475 | 0.0480 | 4 | |
| PLX-4720 | LOXIMVI | 1.0000 | uM | 24 | hr | 2885 | 112 | 1.1324 | 1.0351 | 0.0388 | 0.0507 | 1 |
| PLX-4720 | LOXIMVI | 1.0000 | uM | 24 | hr | 2943 | 179 | 1.1287 | 1.0351 | 0.0608 | 0.0507 | 2 |
| PLX-4720 | LOXIMVI | 1.0000 | uM | 24 | hr | 2377 | 126 | 0.9192 | 1.0351 | 0.0530 | 0.0507 | 3 |
| PLX-4720 | LOXIMVI | 1.0000 | uM | 24 | hr | 2475 | 124 | 0.9601 | 1.0351 | 0.0501 | 0.0507 | 4 |
| PLX-4720 | LOXIMVI | 1.0000 | uM | 48 | hr | 2036 | 1.2754 | 1.3764 | 0.0683 | 0.0654 | 1 | |
| PLX-4720 | LOXIMVI | 1.0000 | uM | 48 | hr | 2145 | 1.3466 | 1.3764 | 0.0662 | 0.0654 | 2 | |
| PLX-4720 | LOXIMVI | 1.0000 | uM | 48 | hr | 2397 | 1.4824 | 1.3764 | 0.0801 | 0.0654 | 3 | |
| PLX-4720 | LOXIMVI | 1.0000 | uM | 48 | hr | 2187 | 1.4011 | 1.3764 | 0.0471 | 0.0654 | 4 | |
| PLX-4720 | LOXIMVI | 1.0000 | uM | 72 | hr | 3162 | 1.7961 | 1.7824 | 0.0569 | 0.0542 | 1 | |
| PLX-4720 | LOXIMVI | 1.0000 | uM | 72 | hr | 3330 | 1.8961 | 1.7824 | 0.0547 | 0.0542 | 2 | |
| PLX-4720 | LOXIMVI | 1.0000 | uM | 72 | hr | 2618 | 1.4980 | 1.7824 | 0.0500 | 0.0542 | 3 |