Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB590885 | LOXIMVI | 3.1600 | uM | 72 | hr | 3106 | 1.7648 | 1.5711 | 0.0567 | 0.0628 | 1 | |
| SB590885 | LOXIMVI | 3.1600 | uM | 72 | hr | 2844 | 1.6118 | 1.5711 | 0.0591 | 0.0628 | 2 | |
| SB590885 | LOXIMVI | 3.1600 | uM | 72 | hr | 2497 | 1.4022 | 1.5711 | 0.0677 | 0.0628 | 3 | |
| SB590885 | LOXIMVI | 3.1600 | uM | 72 | hr | 2682 | 1.5058 | 1.5711 | 0.0679 | 0.0628 | 4 | |
| PLX-4720 | LOXIMVI | 0.0032 | uM | 24 | hr | 2703 | 139 | 1.0470 | 0.9169 | 0.0514 | 0.0547 | 1 |
| PLX-4720 | LOXIMVI | 0.0032 | uM | 24 | hr | 2469 | 151 | 0.9466 | 0.9169 | 0.0612 | 0.0547 | 2 |
| PLX-4720 | LOXIMVI | 0.0032 | uM | 24 | hr | 2088 | 118 | 0.8045 | 0.9169 | 0.0565 | 0.0547 | 3 |
| PLX-4720 | LOXIMVI | 0.0032 | uM | 24 | hr | 2240 | 111 | 0.8694 | 0.9169 | 0.0496 | 0.0547 | 4 |
| PLX-4720 | LOXIMVI | 0.0032 | uM | 48 | hr | 1793 | 1.0743 | 1.0011 | 0.1088 | 0.1106 | 1 | |
| PLX-4720 | LOXIMVI | 0.0032 | uM | 48 | hr | 1638 | 0.9843 | 1.0011 | 0.1062 | 0.1106 | 2 | |
| PLX-4720 | LOXIMVI | 0.0032 | uM | 48 | hr | 1815 | 1.0649 | 1.0011 | 0.1273 | 0.1106 | 3 | |
| PLX-4720 | LOXIMVI | 0.0032 | uM | 48 | hr | 1456 | 0.8807 | 1.0011 | 0.1003 | 0.1106 | 4 | |
| PLX-4720 | LOXIMVI | 0.0032 | uM | 72 | hr | 2195 | 1.0438 | 1.0965 | 0.2105 | 0.2111 | 1 | |
| PLX-4720 | LOXIMVI | 0.0032 | uM | 72 | hr | 1843 | 0.8740 | 1.0965 | 0.2127 | 0.2111 | 2 | |
| PLX-4720 | LOXIMVI | 0.0032 | uM | 72 | hr | 2279 | 1.0733 | 1.0965 | 0.2181 | 0.2111 | 3 | |
| PLX-4720 | LOXIMVI | 0.0032 | uM | 72 | hr | 2906 | 1.3950 | 1.0965 | 0.2030 | 0.2111 | 4 | |
| PLX-4720 | LOXIMVI | 0.0100 | uM | 24 | hr | 2913 | 135 | 1.1344 | 0.9685 | 0.0463 | 0.0479 | 1 |
| PLX-4720 | LOXIMVI | 0.0100 | uM | 24 | hr | 3049 | 244 | 1.1455 | 0.9685 | 0.0800 | 0.0479 | 2 |
| PLX-4720 | LOXIMVI | 0.0100 | uM | 24 | hr | 2112 | 71 | 0.8335 | 0.9685 | 0.0336 | 0.0479 | 3 |
| PLX-4720 | LOXIMVI | 0.0100 | uM | 24 | hr | 1924 | 61 | 0.7608 | 0.9685 | 0.0317 | 0.0479 | 4 |
| PLX-4720 | LOXIMVI | 0.0100 | uM | 48 | hr | 2424 | 1.4824 | 1.4048 | 0.0903 | 0.0809 | 1 | |
| PLX-4720 | LOXIMVI | 0.0100 | uM | 48 | hr | 2327 | 1.4280 | 1.4048 | 0.0872 | 0.0809 | 2 | |
| PLX-4720 | LOXIMVI | 0.0100 | uM | 48 | hr | 1974 | 1.2162 | 1.4048 | 0.0836 | 0.0809 | 3 | |
| PLX-4720 | LOXIMVI | 0.0100 | uM | 48 | hr | 2368 | 1.4925 | 1.4048 | 0.0625 | 0.0809 | 4 | |
| PLX-4720 | LOXIMVI | 0.0100 | uM | 72 | hr | 3109 | 1.6461 | 1.8163 | 0.1209 | 0.1445 | 1 |