Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | WM-115 | 0.3160 | uM | 48 | hr | 721 | 27 | 1.4011 | 1.6676 | 0.0374 | 0.0333 | 3 |
| PLX-4720 | WM-115 | 0.3160 | uM | 48 | hr | 651 | 19 | 1.2759 | 1.6676 | 0.0292 | 0.0333 | 4 |
| PLX-4720 | WM-115 | 0.3160 | uM | 72 | hr | 2749 | 121 | 0.8669 | 0.8596 | 0.0440 | 0.0415 | 1 |
| PLX-4720 | WM-115 | 0.3160 | uM | 72 | hr | 2727 | 104 | 0.8652 | 0.8596 | 0.0381 | 0.0415 | 2 |
| PLX-4720 | WM-115 | 0.3160 | uM | 72 | hr | 2722 | 121 | 0.8580 | 0.8596 | 0.0445 | 0.0415 | 3 |
| PLX-4720 | WM-115 | 0.3160 | uM | 72 | hr | 2678 | 106 | 0.8484 | 0.8596 | 0.0396 | 0.0415 | 4 |
| PLX-4720 | WM-115 | 1.0000 | uM | 24 | hr | 691 | 38 | 1.2471 | 1.0218 | 0.0550 | 0.0643 | 1 |
| PLX-4720 | WM-115 | 1.0000 | uM | 24 | hr | 315 | 20 | 0.5634 | 1.0218 | 0.0635 | 0.0643 | 2 |
| PLX-4720 | WM-115 | 1.0000 | uM | 24 | hr | 688 | 43 | 1.2319 | 1.0218 | 0.0625 | 0.0643 | 3 |
| PLX-4720 | WM-115 | 1.0000 | uM | 24 | hr | 592 | 45 | 1.0447 | 1.0218 | 0.0760 | 0.0643 | 4 |
| PLX-4720 | WM-115 | 1.0000 | uM | 48 | hr | 714 | 37 | 1.3668 | 1.2446 | 0.0518 | 0.0466 | 1 |
| PLX-4720 | WM-115 | 1.0000 | uM | 48 | hr | 777 | 37 | 1.4940 | 1.2446 | 0.0476 | 0.0466 | 2 |
| PLX-4720 | WM-115 | 1.0000 | uM | 48 | hr | 477 | 20 | 0.9226 | 1.2446 | 0.0419 | 0.0466 | 3 |
| PLX-4720 | WM-115 | 1.0000 | uM | 48 | hr | 620 | 28 | 1.1952 | 1.2446 | 0.0452 | 0.0466 | 4 |
| PLX-4720 | WM-115 | 1.0000 | uM | 72 | hr | 1977 | 259 | 0.5667 | 0.5943 | 0.1310 | 0.1294 | 1 |
| PLX-4720 | WM-115 | 1.0000 | uM | 72 | hr | 1926 | 230 | 0.5595 | 0.5943 | 0.1194 | 0.1294 | 2 |
| PLX-4720 | WM-115 | 1.0000 | uM | 72 | hr | 2251 | 306 | 0.6416 | 0.5943 | 0.1359 | 0.1294 | 3 |
| PLX-4720 | WM-115 | 1.0000 | uM | 72 | hr | 2126 | 279 | 0.6093 | 0.5943 | 0.1312 | 0.1294 | 4 |
| PLX-4720 | WM-115 | 3.1600 | uM | 24 | hr | 593 | 56 | 1.0256 | 1.1378 | 0.0944 | 0.0673 | 1 |
| PLX-4720 | WM-115 | 3.1600 | uM | 24 | hr | 566 | 55 | 0.9759 | 1.1378 | 0.0972 | 0.0673 | 2 |
| PLX-4720 | WM-115 | 3.1600 | uM | 24 | hr | 749 | 30 | 1.3732 | 1.1378 | 0.0401 | 0.0673 | 3 |
| PLX-4720 | WM-115 | 3.1600 | uM | 24 | hr | 640 | 24 | 1.1765 | 1.1378 | 0.0375 | 0.0673 | 4 |
| PLX-4720 | WM-115 | 3.1600 | uM | 48 | hr | 490 | 61 | 0.8661 | 0.7919 | 0.1245 | 0.1219 | 1 |
| PLX-4720 | WM-115 | 3.1600 | uM | 48 | hr | 465 | 48 | 0.8419 | 0.7919 | 0.1032 | 0.1219 | 2 |
| PLX-4720 | WM-115 | 3.1600 | uM | 48 | hr | 425 | 57 | 0.7430 | 0.7919 | 0.1341 | 0.1219 | 3 |