Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | WM-115 | 0.0316 | uM | 48 | hr | 689 | 22 | 1.3466 | 1.3188 | 0.0319 | 0.0356 | 2 |
| PLX-4720 | WM-115 | 0.0316 | uM | 48 | hr | 720 | 30 | 1.3930 | 1.3188 | 0.0417 | 0.0356 | 3 |
| PLX-4720 | WM-115 | 0.0316 | uM | 48 | hr | 485 | 15 | 0.9489 | 1.3188 | 0.0309 | 0.0356 | 4 |
| PLX-4720 | WM-115 | 0.0316 | uM | 72 | hr | 3255 | 91 | 1.0437 | 1.0335 | 0.0280 | 0.0268 | 1 |
| PLX-4720 | WM-115 | 0.0316 | uM | 72 | hr | 3372 | 100 | 1.0793 | 1.0335 | 0.0297 | 0.0268 | 2 |
| PLX-4720 | WM-115 | 0.0316 | uM | 72 | hr | 3175 | 75 | 1.0226 | 1.0335 | 0.0236 | 0.0268 | 3 |
| PLX-4720 | WM-115 | 0.0316 | uM | 72 | hr | 3076 | 80 | 0.9883 | 1.0335 | 0.0260 | 0.0268 | 4 |
| PLX-4720 | WM-115 | 0.1000 | uM | 24 | hr | 599 | 21 | 1.1039 | 1.4443 | 0.0351 | 0.0369 | 1 |
| PLX-4720 | WM-115 | 0.1000 | uM | 24 | hr | 680 | 29 | 1.2433 | 1.4443 | 0.0426 | 0.0369 | 2 |
| PLX-4720 | WM-115 | 0.1000 | uM | 24 | hr | 912 | 35 | 1.6749 | 1.4443 | 0.0384 | 0.0369 | 3 |
| PLX-4720 | WM-115 | 0.1000 | uM | 24 | hr | 949 | 30 | 1.7552 | 1.4443 | 0.0316 | 0.0369 | 4 |
| PLX-4720 | WM-115 | 0.1000 | uM | 48 | hr | 1259 | 37 | 2.4671 | 1.8266 | 0.0294 | 0.0312 | 1 |
| PLX-4720 | WM-115 | 0.1000 | uM | 48 | hr | 939 | 29 | 1.8372 | 1.8266 | 0.0309 | 0.0312 | 2 |
| PLX-4720 | WM-115 | 0.1000 | uM | 48 | hr | 1004 | 25 | 1.9765 | 1.8266 | 0.0249 | 0.0312 | 3 |
| PLX-4720 | WM-115 | 0.1000 | uM | 48 | hr | 529 | 21 | 1.0256 | 1.8266 | 0.0397 | 0.0312 | 4 |
| PLX-4720 | WM-115 | 0.1000 | uM | 72 | hr | 3284 | 89 | 1.0539 | 1.0603 | 0.0271 | 0.0303 | 1 |
| PLX-4720 | WM-115 | 0.1000 | uM | 72 | hr | 3377 | 108 | 1.0783 | 1.0603 | 0.0320 | 0.0303 | 2 |
| PLX-4720 | WM-115 | 0.1000 | uM | 72 | hr | 3236 | 113 | 1.0302 | 1.0603 | 0.0349 | 0.0303 | 3 |
| PLX-4720 | WM-115 | 0.1000 | uM | 72 | hr | 3361 | 91 | 1.0787 | 1.0603 | 0.0271 | 0.0303 | 4 |
| PLX-4720 | WM-115 | 0.3160 | uM | 24 | hr | 766 | 26 | 1.4133 | 1.5833 | 0.0339 | 0.0371 | 1 |
| PLX-4720 | WM-115 | 0.3160 | uM | 24 | hr | 649 | 22 | 1.1975 | 1.5833 | 0.0339 | 0.0371 | 2 |
| PLX-4720 | WM-115 | 0.3160 | uM | 24 | hr | 1022 | 43 | 1.8697 | 1.5833 | 0.0421 | 0.0371 | 3 |
| PLX-4720 | WM-115 | 0.3160 | uM | 24 | hr | 1009 | 39 | 1.8526 | 1.5833 | 0.0387 | 0.0371 | 4 |
| PLX-4720 | WM-115 | 0.3160 | uM | 48 | hr | 1140 | 37 | 2.2268 | 1.6676 | 0.0325 | 0.0333 | 1 |
| PLX-4720 | WM-115 | 0.3160 | uM | 48 | hr | 906 | 31 | 1.7665 | 1.6676 | 0.0342 | 0.0333 | 2 |