Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB590885 | COLO 858 | 1.0000 | uM | 72 | hr | 1540 | 408 | 0.4112 | 0.3809 | 0.2649 | 0.2676 | 4 |
| SB590885 | COLO 858 | 3.1600 | uM | 24 | hr | 3538 | 464 | 1.0268 | 0.8106 | 0.1312 | 0.1298 | 1 |
| SB590885 | COLO 858 | 3.1600 | uM | 24 | hr | 3425 | 396 | 1.0118 | 0.8106 | 0.1156 | 0.1298 | 2 |
| SB590885 | COLO 858 | 3.1600 | uM | 24 | hr | 2057 | 294 | 0.5889 | 0.8106 | 0.1429 | 0.1298 | 3 |
| SB590885 | COLO 858 | 3.1600 | uM | 24 | hr | 2115 | 274 | 0.6150 | 0.8106 | 0.1296 | 0.1298 | 4 |
| SB590885 | COLO 858 | 3.1600 | uM | 48 | hr | 1722 | 511 | 0.2767 | 0.2774 | 0.2968 | 0.3405 | 1 |
| SB590885 | COLO 858 | 3.1600 | uM | 48 | hr | 1902 | 641 | 0.2881 | 0.2774 | 0.3370 | 0.3405 | 2 |
| SB590885 | COLO 858 | 3.1600 | uM | 48 | hr | 1862 | 756 | 0.2527 | 0.2774 | 0.4060 | 0.3405 | 3 |
| SB590885 | COLO 858 | 3.1600 | uM | 48 | hr | 1886 | 608 | 0.2920 | 0.2774 | 0.3224 | 0.3405 | 4 |
| SB590885 | COLO 858 | 3.1600 | uM | 72 | hr | 1352 | 608 | 0.2702 | 0.2903 | 0.4497 | 0.4242 | 1 |
| SB590885 | COLO 858 | 3.1600 | uM | 72 | hr | 1325 | 567 | 0.2753 | 0.2903 | 0.4279 | 0.4242 | 2 |
| SB590885 | COLO 858 | 3.1600 | uM | 72 | hr | 1463 | 614 | 0.3084 | 0.2903 | 0.4197 | 0.4242 | 3 |
| SB590885 | COLO 858 | 3.1600 | uM | 72 | hr | 1409 | 563 | 0.3073 | 0.2903 | 0.3996 | 0.4242 | 4 |
| PLX-4720 | COLO 858 | 0.0032 | uM | 24 | hr | 3717 | 194 | 1.1768 | 1.0285 | 0.0522 | 0.0469 | 1 |
| PLX-4720 | COLO 858 | 0.0032 | uM | 24 | hr | 4211 | 200 | 1.3398 | 1.0285 | 0.0475 | 0.0469 | 2 |
| PLX-4720 | COLO 858 | 0.0032 | uM | 24 | hr | 1776 | 73 | 0.5689 | 1.0285 | 0.0411 | 0.0469 | 3 |
| PLX-4720 | COLO 858 | 0.0032 | uM | 24 | hr | 4 | ||||||
| PLX-4720 | COLO 858 | 0.0032 | uM | 48 | hr | 4567 | 244 | 0.9877 | 0.9682 | 0.0534 | 0.0522 | 1 |
| PLX-4720 | COLO 858 | 0.0032 | uM | 48 | hr | 4210 | 206 | 0.9149 | 0.9682 | 0.0489 | 0.0522 | 2 |
| PLX-4720 | COLO 858 | 0.0032 | uM | 48 | hr | 4632 | 253 | 1.0005 | 0.9682 | 0.0546 | 0.0522 | 3 |
| PLX-4720 | COLO 858 | 0.0032 | uM | 48 | hr | 4476 | 232 | 0.9697 | 0.9682 | 0.0518 | 0.0522 | 4 |
| PLX-4720 | COLO 858 | 0.0032 | uM | 72 | hr | 3110 | 290 | 1.0243 | 1.1298 | 0.0932 | 0.0883 | 1 |
| PLX-4720 | COLO 858 | 0.0032 | uM | 72 | hr | 3189 | 273 | 1.0592 | 1.1298 | 0.0856 | 0.0883 | 2 |
| PLX-4720 | COLO 858 | 0.0032 | uM | 72 | hr | 3946 | 363 | 1.3015 | 1.1298 | 0.0920 | 0.0883 | 3 |
| PLX-4720 | COLO 858 | 0.0032 | uM | 72 | hr | 3404 | 281 | 1.1344 | 1.1298 | 0.0826 | 0.0883 | 4 |