Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
PLX-4720 COLO 858 1.0000
uM
 24
hr
 2366 276 0.6981 0.9459 0.1167 0.1081 3
PLX-4720 COLO 858 1.0000
uM
 24
hr
 2324 263 0.6885 0.9459 0.1132 0.1081 4
PLX-4720 COLO 858 1.0000
uM
 48
hr
 2045 279 0.4035 0.4070 0.1364 0.1839 1
PLX-4720 COLO 858 1.0000
uM
 48
hr
 2238 304 0.4419 0.4070 0.1358 0.1839 2
PLX-4720 COLO 858 1.0000
uM
 48
hr
 2029 413 0.3692 0.4070 0.2036 0.1839 3
PLX-4720 COLO 858 1.0000
uM
 48
hr
 2445 635 0.4136 0.4070 0.2597 0.1839 4
PLX-4720 COLO 858 1.0000
uM
 72
hr
 1332 267 0.3868 0.4174 0.2005 0.1830 1
PLX-4720 COLO 858 1.0000
uM
 72
hr
 1282 267 0.3687 0.4174 0.2083 0.1830 2
PLX-4720 COLO 858 1.0000
uM
 72
hr
 1586 263 0.4806 0.4174 0.1658 0.1830 3
PLX-4720 COLO 858 1.0000
uM
 72
hr
 1417 223 0.4337 0.4174 0.1574 0.1830 4
PLX-4720 COLO 858 3.1600
uM
 24
hr
 3515 504 1.0058 0.8080 0.1434 0.1544 1
PLX-4720 COLO 858 3.1600
uM
 24
hr
 3632 527 1.0372 0.8080 0.1451 0.1544 2
PLX-4720 COLO 858 3.1600
uM
 24
hr
 2153 364 0.5976 0.8080 0.1691 0.1544 3
PLX-4720 COLO 858 3.1600
uM
 24
hr
 2108 337 0.5916 0.8080 0.1599 0.1544 4
PLX-4720 COLO 858 3.1600
uM
 48
hr
 1860 509 0.3087 0.3057 0.2737 0.3229 1
PLX-4720 COLO 858 3.1600
uM
 48
hr
 1908 586 0.3021 0.3057 0.3071 0.3229 2
PLX-4720 COLO 858 3.1600
uM
 48
hr
 2256 812 0.3299 0.3057 0.3599 0.3229 3
PLX-4720 COLO 858 3.1600
uM
 48
hr
 1903 668 0.2822 0.3057 0.3510 0.3229 4
PLX-4720 COLO 858 3.1600
uM
 72
hr
 1183 457 0.2637 0.2732 0.3863 0.3742 1
PLX-4720 COLO 858 3.1600
uM
 72
hr
 1101 421 0.2470 0.2732 0.3824 0.3742 2
PLX-4720 COLO 858 3.1600
uM
 72
hr
 1114 422 0.2514 0.2732 0.3788 0.3742 3
PLX-4720 COLO 858 3.1600
uM
 72
hr
 1400 489 0.3309 0.2732 0.3493 0.3742 4
AZ-628 COLO 858 0.0032
uM
 24
hr
 3916 201 1.2409 0.9225 0.0513 0.0485 1
AZ-628 COLO 858 0.0032
uM
 24
hr
 4126 227 1.3024 0.9225 0.0550 0.0485 2
AZ-628 COLO 858 0.0032
uM
 24
hr
 1827 76 0.5849 0.9225 0.0416 0.0485 3