Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | LOXIMVI | 0.0100 | uM | 72 | hr | 3093 | 1.6178 | 1.8163 | 0.1316 | 0.1445 | 2 | |
| PLX-4720 | LOXIMVI | 0.0100 | uM | 72 | hr | 3315 | 1.6558 | 1.8163 | 0.1707 | 0.1445 | 3 | |
| PLX-4720 | LOXIMVI | 0.0100 | uM | 72 | hr | 4606 | 2.3454 | 1.8163 | 0.1546 | 0.1445 | 4 | |
| PLX-4720 | LOXIMVI | 0.0316 | uM | 24 | hr | 2934 | 127 | 1.1463 | 1.0255 | 0.0433 | 0.0396 | 1 |
| PLX-4720 | LOXIMVI | 0.0316 | uM | 24 | hr | 2988 | 157 | 1.1561 | 1.0255 | 0.0525 | 0.0396 | 2 |
| PLX-4720 | LOXIMVI | 0.0316 | uM | 24 | hr | 2274 | 57 | 0.9053 | 1.0255 | 0.0251 | 0.0396 | 3 |
| PLX-4720 | LOXIMVI | 0.0316 | uM | 24 | hr | 2275 | 85 | 0.8943 | 1.0255 | 0.0374 | 0.0396 | 4 |
| PLX-4720 | LOXIMVI | 0.0316 | uM | 48 | hr | 2411 | 1.5161 | 1.6673 | 0.0647 | 0.0585 | 1 | |
| PLX-4720 | LOXIMVI | 0.0316 | uM | 48 | hr | 3051 | 1.9672 | 1.6673 | 0.0410 | 0.0585 | 2 | |
| PLX-4720 | LOXIMVI | 0.0316 | uM | 48 | hr | 2413 | 1.5261 | 1.6673 | 0.0593 | 0.0585 | 3 | |
| PLX-4720 | LOXIMVI | 0.0316 | uM | 48 | hr | 2652 | 1.6599 | 1.6673 | 0.0690 | 0.0585 | 4 | |
| PLX-4720 | LOXIMVI | 0.0316 | uM | 72 | hr | 3344 | 1.8648 | 2.3076 | 0.0742 | 0.0740 | 1 | |
| PLX-4720 | LOXIMVI | 0.0316 | uM | 72 | hr | 4122 | 2.3117 | 2.3076 | 0.0689 | 0.0740 | 2 | |
| PLX-4720 | LOXIMVI | 0.0316 | uM | 72 | hr | 4778 | 2.6900 | 2.3076 | 0.0653 | 0.0740 | 3 | |
| PLX-4720 | LOXIMVI | 0.0316 | uM | 72 | hr | 4302 | 2.3641 | 2.3076 | 0.0876 | 0.0740 | 4 | |
| PLX-4720 | LOXIMVI | 0.1000 | uM | 24 | hr | 3036 | 170 | 1.1704 | 1.0963 | 0.0560 | 0.0507 | 1 |
| PLX-4720 | LOXIMVI | 0.1000 | uM | 24 | hr | 3058 | 154 | 1.1859 | 1.0963 | 0.0504 | 0.0507 | 2 |
| PLX-4720 | LOXIMVI | 0.1000 | uM | 24 | hr | 2540 | 127 | 0.9854 | 1.0963 | 0.0500 | 0.0507 | 3 |
| PLX-4720 | LOXIMVI | 0.1000 | uM | 24 | hr | 2680 | 124 | 1.0438 | 1.0963 | 0.0463 | 0.0507 | 4 |
| PLX-4720 | LOXIMVI | 0.1000 | uM | 48 | hr | 2898 | 1.8583 | 1.7166 | 0.0462 | 0.0482 | 1 | |
| PLX-4720 | LOXIMVI | 0.1000 | uM | 48 | hr | 2705 | 1.7420 | 1.7166 | 0.0421 | 0.0482 | 2 | |
| PLX-4720 | LOXIMVI | 0.1000 | uM | 48 | hr | 2370 | 1.5026 | 1.7166 | 0.0570 | 0.0482 | 3 | |
| PLX-4720 | LOXIMVI | 0.1000 | uM | 48 | hr | 2754 | 1.7635 | 1.7166 | 0.0476 | 0.0482 | 4 | |
| PLX-4720 | LOXIMVI | 0.1000 | uM | 72 | hr | 3657 | 2.1027 | 2.4826 | 0.0454 | 0.0395 | 1 | |
| PLX-4720 | LOXIMVI | 0.1000 | uM | 72 | hr | 4363 | 2.5297 | 2.4826 | 0.0374 | 0.0395 | 2 |