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Ibrutinib KiNativ -- single dose experiment
- Dataset (ID:20214)
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Small Molecules Studied
Cell Lines Studied
Proteins Studied
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Small molecules
Cells
Proteins
10129:Ibrutinib
51097:BCWM.1
51098:MWCL.1
200633:ABL,ARG
200634:ABL,ARG
200635:ACK
200639:AMPKa1,AMPKa2
200641:ARAF
200643:ATR
200647:BRAF
200650:CaMK2g
200653:CASK
200654:CDC2
200656:CDK11,CDK8
200658:CDK2
200659:CDK4
200662:CDK6
200663:CDK7
200664:CDK9
200667:KC1A
200669:CSK
200672:DNAPK
200674:DNAPK
200677:eEF2K
200681:MK03
200682:Erk5
200686:FER
200687:FYN,SRC,YES
200690:GCK
200691:GCN2_domain2
200693:GSK3A
200694:GSK3B
200695:IKKA
200696:IKKB
200699:ILK
200700:IRAK1
200701:IRAK4
200702:IRE1
200703:ITPK1
200704:JAK1
200706:JAK1_domain2
200707:JNK1,JNK2,JNK3
200710:KHS1
200711:LATS1
200712:LKB1
200714:LOK
200717:LRRK2
200718:MAP2K1
200719:MAP2K1,MAP2K2
200722:MAP2K3
200724:MAP2K4
200725:MAP2K5
200726:MAP2K6
200729:MP2K7
200730:MAP3K1
200731:M3K2
200732:M3K2,MAP3K3
200733:MAP3K3
200734:MAP3K4
200736:MAP3K7,TAK1
200739:MARK2,MARK3
200740:MARK3
200741:MAST1,MAST2
200743:MAST3
200744:MASTL
200746:MLK3
200747:MLKL
200750:MSK1_domain1
200751:MST1
200755:MST2
200756:MST3
200759:MST4,YSK1
200761:NDR1
200765:NDR2
200767:NEK1
200768:NEK6,NEK7
200770:NEK7
200771:NEK8
200774:NEK9
200776:OSR1
200777:p38d,p38g
200779:KS6B1
200782:KS6B2
200785:PCTAIRE2,PCTAIRE3
200787:CDK14
200788:PHKg2
200789:PI4KA,PI4KAP2
200790:PI4KB
200793:PIK3C3
200795:PIK3CB
200797:PIP4K2A
200799:PI42C
200800:FYV1
200801:PITSLRE
200809:PKR
200810:PLK1
200812:PRPK
200813:RAF1
200814:ROCK1,ROCK2
200815:RSK1,RSK2,RSK3_domain1
200819:RSK1_domain2
200821:RSK2_domain2
200824:RSK3_domain1
200825:RSKL1_domain1
200826:SGK3
200829:SLK
200830:SMG1
200833:STLK5
200834:TAO1,TAOK3
200835:TAOK2
200836:TBK1
200837:TLK1
200839:ULK3
200840:VRK2
200841:WEE1
200842:Wnk1,Wnk2,Wnk3
200847:ZC1/HGK,ZC2/TNIK,ZC3/MINK
200848:ZC2/TNIK
200877:BARK1
200881:BTK
200882:CAMK1D
200886:CaMKK2
200890:CDK5
200895:CHK1
200896:CHK2
200907:DGKA
200916:FES
200918:FGR
200921:FRAP1
200927:HPK1
200933:IKKE
200937:KSR1,KSR2
200940:LYN
200944:MAP3K5
200949:MARK3,MARK4
200950:MASTL
200958:MST4
200960:NEK3
200961:NEK4
200965:p38a
200967:MK14
200969:PAN3
200973:PEK
200975:PIK3C2B
200977:PIK3CD
200978:PIK3CG
200988:PKD3
200997:FAK2
201013:SRPK1
201014:SRPK1/2
201016:STLK6
201022:TLK1/2
201037:LATS2
201043:PRP4
201045:RSK1 domain1
201049:CK2a2
201054:EPHB2
201057:JAK3 domain2
201061:MK11
201062:PDK1
201064:PKD2
201065:RIPK3
201069:SYK
201071:ULK1
201072:AurB
201075:MYO3A,MYO3B
201076:SNRK
201077:TEC
201080:AurA
201088:MLK4
201090:MSK2 domain1
201094:PKN1
201096:RIPK2
201098:RSK4 domain1
201163:BLK
201167:KCC4
201172:CDK16
201186:EPHB1
201192:MK01
201197:FRK
201209:KC1G2
201210:KCC2D
201215:KSR1
201217:LCK
201230:M3K6
201233:MARK4
201235:MELK
201243:NEK2
201262:RSK2 domain1
201268:STK33
201276:TYK2(Kin.Dom.2)
201279:Wnk1,Wnk2
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Small Molecule
Cell Line
Protein
Sequence
Labeling Site
% Inhibition
Assay compound conc
Conc unit
Ibrutinib
MWCL.1
MK14
QELNKTIWEVPER
Other
-16.68433891
1
uM
Ibrutinib
BCWM.1
MK14
QELNKTIWEVPER
Other
6.71455834
1
uM
Ibrutinib
BCWM.1
MK11
QELNKTVWEVPQR
Other
-0.386101983
1
uM
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