PCI-32765 KiNativ -- single dose experiment - Dataset (ID:20206)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | Ramos (RA 1) | TLK1 | YLNEIKPPIIHYDLKPGNILLVDGTACGEIK | Lys2 | -41.6 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | TLK1/2 | YLNEIKPPIIHYDLKPGNILLVNGTACGEIK | Lys2 | -2.7 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | ULK3 | EVVAIKCVAK | Lys1 | -3.5 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MLTK | WISQDKEVAVKK | Lys1 | 28.3 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | ZC1/HGK,ZC2/TNIK,ZC3/MINK | DIKGQNVLLTENAEVK | Lys2 | -45.9 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | BLK | IIDSEYTAQEGAKFPIK | Activation Loop | >99 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | KCC2D | IPTGQEYAAKIINTKK | Lys1 | 24.6 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | KC1G1 | DVKPENFLIGR | Lys2 | -1.8 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | KC1G2 | DVKPENFLVGRPGTK | Lys2 | -17.8 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | LCK | EGAKFPIKWTAPEAINYGTFTIK | Activation Loop | -2.6 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MARK1,MARK2 | EVAVKIIDK | Lys1 | 25.8 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | KPCI | DLKLDNVLLDSEGHIK | Lys2 | 19.2 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | ZAP70 | ISDFGLSKALGADDSYYTAR | Activation Loop | 10.5 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | KCC4 | DLKPENLLYATPAPDAPLK | Lys2 | -3.0 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MK01 | DLKPSNLLLNTTCDLK | Lys2 | 21.5 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | RSK2 domain1 | DLKPENILLDEEGHIKLTDFGLSKESIDHEK | Lys2 | -17.1 | 1 | uM |