HKI-272 KINOMEscan-2 - Dataset (ID:20195)
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200035 | AKT2 | 200035 | P31751 | V-akt murine thymoma viral oncogene homolog 2; AKT2; Akt2/PKBb; PKBb; PKBBETA; PRKBB; RAC-BETA | KINOMEscan | Wild Type; Partial length | |||
| 200036 | AKT3 | 200036 | Q9Y243 | V-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); AKT3; Akt3/PKBg; DKFZp434N0250; PKBg; PKB-GAMMA; PRKBG; RAC-gamma; RAC-PK-gamma; STK-2 | KINOMEscan | Wild Type; Partial length | |||
| 200037 | ALK | 200037 | Q9UM73 | Anaplastic lymphoma receptor tyrosine kinase; ALK; CD246; NBLST3; TFG/ALK | KINOMEscan | Wild Type; Partial length | |||
| 200038 | AMPK-alpha1 | 200038 | Q13131 | Protein kinase, AMP-activated, alpha 2 catalytic subunit; AMPK; AMPKa1; AMPK-alpha1; MGC33776; MGC57364; PRKAA1 | KINOMEscan | Wild Type; Partial length | |||
| 200039 | AMPK-alpha2 | 200039 | P54646 | Protein kinase, AMP-activated, alpha 2 catalytic subunit; AMPK; AMPK2; AMPKa2; AMPK-alpha2; PRKAA; PRKAA2 | KINOMEscan | Wild Type; Partial length | |||
| 200040 | ANKK1 | 200040 | Q8NFD2 | Ankyrin repeat and kinase domain containing 1; ANKK1; PKK2; SgK288 | KINOMEscan | Wild Type; Partial length | |||
| 200041 | NUAK1 | 200041 | O60285 | NUAK family, SNF1-like kinase, 1; ARK5; KIAA0537; NUAK1 | KINOMEscan | Wild Type; Partial length | |||
| 200042 | M3K5 | 200042 | Q99683 | Mitogen-activated protein kinase kinase kinase 5; ASK; ASK/MAP3K5; ASK1; MAP3K5; MAPKKK5; MEKK5 | KINOMEscan | Wild Type; Partial length | |||
| 200043 | M3K6 | 200043 | O95382 | Mitogen-activated protein kinase kinase kinase 6; ASK2; MAP3K6; MAPKKK6; MEKK6; MEKK6/MAP3K6; MGC125653; MGC20114 | KINOMEscan | Wild Type; Partial length | |||
| 200044 | AURKA | 200044 | O14965 | Aurora kinase A; AIK; AIRK1; ARK1; Aur2; AURA; AurA/Aur2; AURKA; AURORA2; Aurora-A; Ayk1; BTAK; IAK; IAK1; MGC34538; STK15; STK6; STK7 | KINOMEscan | Wild Type; Partial length | |||
| 200045 | AURKB | 200045 | Q96GD4 | Aurora kinase B; AIK2; AIM1; AIM-1; ARK2; Aur1; AurB; AurB/Aur1; AURKB; aurkb-sv1; aurkb-sv2; IPL1; STK12; STK5 | KINOMEscan | Wild Type; Partial length | |||
| 200046 | AURKC | 200046 | Q9UQB9 | Aurora kinase C; AIE2; AIK3; ARK3; Aur3; AurC; AurC/Aur3; AURKC; aurora-C; STK13 | KINOMEscan | Wild Type; Full length | |||
| 200047 | AXL | 200047 | P30530 | AXL receptor tyrosine kinase; AXL; JTK11; UFO | KINOMEscan | Wild Type; Partial length | |||
| 200048 | BIKE | 200048 | Q9NSY1 | BMP2 inducible kinase; BIKE; BMP2K; DKFZp434K0614; DKFZp434P0116; HRIHFB2017 | KINOMEscan | Wild Type; Partial length | |||
| 200049 | BLK | 200049 | P51451 | Tyrosine-protein kinase BLK; B lymphoid tyrosine kinase; BLK; MGC10442 | KINOMEscan | Wild Type; Partial length | |||
| 200050 | BMPR1A | 200050 | P36894 | Bone morphogenetic protein receptor, type IA; 10q23del; ACVRLK3; ALK3; BMPR1A; CD292; SKR5 | KINOMEscan | Wild Type; Partial length | |||
| 200051 | BMPR1B | 200051 | O00238 | Bone morphogenetic protein receptor, type IB; ALK6; ALK-6; BMPR1B; CDw293 | KINOMEscan | Wild Type; Partial length | |||
| 200052 | BMPR2 | 200052 | Q13873 | Bone morphogenetic protein receptor, type II (serine/threonine kinase); BMPR2; BMPR3; BMPR-II; BMR2; BRK-3; FLJ41585; FLJ76945; PPH1; T-ALK | KINOMEscan | Wild Type; Partial length | |||
| 200053 | BMX | 200053 | P51813 | BMX non-receptor tyrosine kinase; BMX; ETK; Etk/BMX; PSCTK2; PSCTK3 | KINOMEscan | Wild Type; Full length | |||
| 200054 | BRAF | 200054 | P15056 | Serine/threonine-protein kinase B-raf; v-raf murine sarcoma viral oncogene homolog B1; BRAF1; RAFB1 | KINOMEscan | Wild Type; Partial length | |||
| 200055 | BRAF(V600E) | 200055 | P15056 | V-raf murine sarcoma viral oncogene homolog B1; BRAF; BRAF1; B-RAF1; FLJ95109; MGC126806; MGC138284; RAFB1 | KINOMEscan | V600E | Mutation (V600E); Partial length | ||
| 200056 | PTK6 | 200056 | Q13882 | Protein tyrosine kinase 6; BRK; FLJ42088; PTK6 | KINOMEscan | Wild Type; Partial length | |||
| 200057 | BRSK1 | 200057 | Q8TDC3 | BR serine/threonine kinase 1; BRSK1; FLJ43009; KIAA1811 | KINOMEscan | Wild Type; Partial length | |||
| 200058 | BRSK2 | 200058 | Q8IWQ3 | BR serine/threonine kinase 2; BRSK2; C11orf7; FLJ41362; PEN11B; SAD1; STK29 | KINOMEscan | Wild Type; Full length | |||
| 200059 | BTK | 200059 | Q06187 | Tyrosine-protein kinase BTK; agammaglobulinemia tyrosine kinase; AGMX1; ATK; BPK | KINOMEscan | Wild Type; Full length |