HKI-272 KINOMEscan-2 - Dataset - HMS LINCS Database

HKI-272 KINOMEscan-2 - Dataset (ID:20195)

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Small molecules	Proteins

Small Molecule	Protein	Kd	Conc unit
Neratinib	AAK1		nM
Neratinib	ABL1(E255K)-phosphorylated		nM
Neratinib	ABL1(F317I)-nonphosphorylated		nM
Neratinib	ABL1(F317I)-phosphorylated		nM
Neratinib	ABL1(F317L)-nonphosphorylated		nM
Neratinib	ABL1(F317L)-phosphorylated		nM
Neratinib	ABL1(H396P)-nonphosphorylated		nM
Neratinib	ABL1(H396P)-phosphorylated		nM
Neratinib	ABL1(M351T)-phosphorylated		nM
Neratinib	ABL1(Q252H)-nonphosphorylated	7100.0	nM
Neratinib	ABL1(Q252H)-phosphorylated	6000.0	nM
Neratinib	ABL1(T315I)-nonphosphorylated		nM
Neratinib	ABL1(T315I)-phosphorylated		nM
Neratinib	ABL1(Y253F)-phosphorylated		nM
Neratinib	ABL1-nonphosphorylated		nM
Neratinib	ABL1-phosphorylated		nM
Neratinib	ABL2		nM
Neratinib	ACVR1		nM
Neratinib	ACVR1B		nM
Neratinib	ACVR2A		nM
Neratinib	ACVR2B		nM
Neratinib	ACVRL1		nM
Neratinib	ADCK3		nM
Neratinib	ADCK4		nM
Neratinib	AKT1		nM