BIBW-2992 KINOMEscan - Dataset (ID:20172)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Protein | Kd | Conc unit |
|---|---|---|---|
| Afatinib | LCK | 570.0 | nM |
| Afatinib | ABL1-phosphorylated | 570.0 | nM |
| Afatinib | ABL1(F317L)-nonphosphorylated | 580.0 | nM |
| Afatinib | ABL1(F317I)-phosphorylated | 750.0 | nM |
| Afatinib | ABL1(Q252H)-nonphosphorylated | 790.0 | nM |
| Afatinib | ABL1(Y253F)-phosphorylated | 830.0 | nM |
| Afatinib | ABL1(T315I)-phosphorylated | 870.0 | nM |
| Afatinib | DYRK1A | 970.0 | nM |
| Afatinib | ABL1(M351T)-phosphorylated | 1200.0 | nM |
| Afatinib | ABL1-nonphosphorylated | 1300.0 | nM |
| Afatinib | MK14 | 1300.0 | nM |
| Afatinib | CSNK1E | 1300.0 | nM |
| Afatinib | PHKG1 | 1300.0 | nM |
| Afatinib | MP2K5 | 1300.0 | nM |
| Afatinib | FRK | 1400.0 | nM |
| Afatinib | FLT3(D835Y) | 1400.0 | nM |
| Afatinib | MKNK2 | 1600.0 | nM |
| Afatinib | FLT3(D835H) | 1800.0 | nM |
| Afatinib | DYRK2 | 1800.0 | nM |
| Afatinib | MKNK1 | 1800.0 | nM |
| Afatinib | JNK3 | 2000.0 | nM |
| Afatinib | MK09 | 2100.0 | nM |
| Afatinib | MET | 2200.0 | nM |
| Afatinib | HCK | 2200.0 | nM |
| Afatinib | DRAK1 | 2300.0 | nM |