Lapatinib KINOMEscan-2 - Dataset (ID:20155)

Proteins Studied

LINCS ID Name HMS LINCS ID UniProt ID Alternative Names Provider Mutation Phosphlorylation State Domain Protein Description
200426 TAK1 200426 O43318
Mitogen-activated protein kinase kinase kinase 7; MAP3K7; MEKK7; TAK1; TGF1a
KINOMEscan Wild Type; Partial length
200427 TAOK1 200427 Q7L7X3
Serine/threonine-protein kinase TAO1; prostate-derived STE20-like kinase 2; hKFC-B; FLJ14314; KIAA1361; MAP3K16; MARKK; PSK2; TAO1; TAOK1
KINOMEscan Wild Type; Partial length
200428 TAOK2 200428 Q9UL54
Serine/threonine-protein kinase TAO2; prostate-derived sterile 20-like kinase 1; hKFC-C; KIAA0881; MAP3K17; PSK; PSK1; PSK1-BETA; TAO2; TAOK2
KINOMEscan Wild Type; Partial length
200429 TAOK3 200429 Q9H2K8
Serine/threonine-protein kinase TAO3; TAO kinase 3; DKFZp666H245; DPK; FLJ31808; JIK; MAP3K18; TAO3
KINOMEscan Wild Type; Partial length
200430 TBK1 200430 Q9UHD2
Serine/threonine-protein kinase TBK1; TANK-binding kinase 1; NF-kappa-B-activating kinase; FLJ11330; NAK; T2K; TBK1
KINOMEscan Wild Type; Full length
200431 TEC 200431 P42680
Tyrosine-protein kinase Tec; MGC126760; MGC126762; PSCTK4; TEC
KINOMEscan Wild Type; Partial length
200432 TESK1 200432 Q15569
Testis-specific kinase 1; TESK1
KINOMEscan Wild Type; Full length
200433 TGFBR1 200433 P36897
Transforming growth factor, beta receptor 1; AAT5; ACVRLK4; ALK5; ALK-5; LDS1A; LDS2A; SKR4; TGFBR1; TGFR-1
KINOMEscan Wild Type; Partial length
200434 TGFBR2 200434 P37173
Transforming growth factor, beta receptor II (70/80kDa); AAT3; FAA3; LDS1B; LDS2B; MFS2; RIIC; TAAD2; TGFbeta-RII; TGFBR2; TGFR-2
KINOMEscan Wild Type; Partial length
200435 TIE1 200435 P35590
Tyrosine-protein kinase receptor Tie-1; tyrosine kinase with immunoglobulin-like and EGF-like domains 1; JTK14; TIE; TIE1
KINOMEscan Wild Type; Partial length
200436 TIE2 200436 Q02763
Angiopoietin-1 receptor; TEK tyrosine kinase, endothelial; CD202B; TEK; TIE2; TIE-2; VMCM; VMCM1
KINOMEscan Wild Type; Partial length
200437 TLK1 200437 Q9UKI8
Serine/threonine-protein kinase tousled-like 1; tousled-like kinase 1; KIAA0137; PKU-beta; TLK1
KINOMEscan Wild Type; Partial length
200438 TLK2 200438 Q86UE8
Serine/threonine-protein kinase tousled-like 2; tousled-like kinase 2; MGC44450; PKU-ALPHA; TLK2
KINOMEscan Wild Type; Partial length
200439 TNIK 200439 Q9UKE5
TRAF2 and NCK interacting kinase; TNIK; TNIK/ZC2; ZC2
KINOMEscan Wild Type; Partial length
200440 TNK1 200440 Q13470
Non-receptor tyrosine-protein kinase TNK1; MGC46193; TNK1
KINOMEscan Wild Type; Full length
200441 TNK2 200441 Q07912
Tyrosine kinase, non-receptor, 2; ACK; ACK1; FLJ44758; FLJ45547; p21cdc42Hs; TNK2
KINOMEscan Wild Type; Partial length
200442 TNNI3K 200442 Q59H18
TNNI3 interacting kinase; CARK; HH498; MGC142099; MGC33828; TNNI3K
KINOMEscan Wild Type; Full length
200443 TRKA 200443 P04629
Neurotrophic tyrosine kinase, receptor, type 1; DKFZp781I14186; MTC; NTRK1; p140-TrkA; TRK; TRK1; TRKA; Trk-A
KINOMEscan Wild Type; Partial length
200444 TRKB 200444 Q16620
Neurotrophic tyrosine kinase, receptor, type 2; GP145-TrkB; NTRK2; TRKB
KINOMEscan Wild Type; Partial length
200445 TRKC 200445 Q16288
Neurotrophic tyrosine kinase, receptor, type 3; gp145(trkC); NTRK3; TRKC
KINOMEscan Wild Type; Partial length
200446 TRPM6 200446 Q9BX84
Transient receptor potential cation channel, subfamily M, member 6; ChaK2; HMGX; HOMG; HOMG1; HSH; TRPM6
KINOMEscan Wild Type; Partial length
200447 TSSK1 200447 Q9BXA7
Testis-specific serine kinase 1B; FKSG81; SPOGA4; STK22D; TSSK1; TSSK1B
KINOMEscan Wild Type; Full length
200448 TTK 200448 P33981
TTK protein kinase; CT96; ESK; FLJ38280; MPS1; MPS1L1; PYT; TTK
KINOMEscan Wild Type; Partial length
200449 TXK 200449 P42681
TXK tyrosine kinase; BTKL; MGC22473; PSCTK5; PTK4; RLK; TKL; TXK
KINOMEscan Wild Type; Partial length
200450 TYK2(JH1domain-catalytic) 200450 P29597
Non-receptor tyrosine-protein kinase TYK2; Tyrosine kinase 2; JTK1; TYK2
KINOMEscan JH1domain-catalytic Wild Type; Partial length