Lapatinib KINOMEscan-2 - Dataset (ID:20155)
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200001 | AAK1 | 200001 | Q2M2I8 | AP2 associated kinase 1; AAK1; DKFZp686F03202; DKFZp686K16132; FLJ23712; FLJ25931; FLJ31060; FLJ42882; FLJ45252; KIAA1048; MGC138170; MGC164568; MGC164570 | KINOMEscan | Wild Type; Partial length | |||
| 200004 | ABL1(E255K)-phosphorylated | 200004 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | E255K | phosphorylated | Mutation (E255K); Partial length | |
| 200006 | ABL1(F317I)-nonphosphorylated | 200006 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317I | nonphosphorylated | Mutation (F317I); Partial length | |
| 200007 | ABL1(F317I)-phosphorylated | 200007 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317I | phosphorylated | Mutation (F317I); Partial length | |
| 200009 | ABL1(F317L)-nonphosphorylated | 200009 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317L | nonphosphorylated | Mutation (F317L); Partial length | |
| 200010 | ABL1(F317L)-phosphorylated | 200010 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317L | phosphorylated | Mutation (F317L); Partial length | |
| 200012 | ABL1(H396P)-nonphosphorylated | 200012 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | H396P | nonphosphorylated | Mutation (H396P); Partial length | |
| 200013 | ABL1(H396P)-phosphorylated | 200013 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | H396P | phosphorylated | Mutation (H396P); Partial length | |
| 200015 | ABL1(M351T)-phosphorylated | 200015 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | M351T | phosphorylated | Mutation (M351T); Partial length | |
| 200017 | ABL1(Q252H)-nonphosphorylated | 200017 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Q252H | nonphosphorylated | Mutation (Q252H); Partial length | |
| 200018 | ABL1(Q252H)-phosphorylated | 200018 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Q252H | phosphorylated | Mutation (Q252H); Partial length | |
| 200020 | ABL1(T315I)-nonphosphorylated | 200020 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | T315I | nonphosphorylated | Mutation (T315I); Partial length | |
| 200021 | ABL1(T315I)-phosphorylated | 200021 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | T315I | phosphorylated | Mutation (T315I); Partial length | |
| 200023 | ABL1(Y253F)-phosphorylated | 200023 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Y253F | phosphorylated | Mutation (Y253F); Partial length | |
| 200024 | ABL1-nonphosphorylated | 200024 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | nonphosphorylated | Wild Type; Partial length | ||
| 200025 | ABL1-phosphorylated | 200025 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | phosphorylated | Wild Type; Partial length | ||
| 200026 | ABL2 | 200026 | P42684 | V-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene); ABL2; ABLL; ARG; FLJ22224; FLJ31718; FLJ41441 | KINOMEscan | Wild Type; Partial length | |||
| 200027 | ACVR1 | 200027 | Q04771 | Activin A receptor, type I; ACTRI; ACVR1; ACVR1A; ACVRLK2; ALK2; FOP; SKR1; TSRI | KINOMEscan | Wild Type; Partial length | |||
| 200028 | ACVR1B | 200028 | P36896 | Activin A receptor, type IB; ACTRIB; ACVR1B; ACVRLK4; ALK4; SKR2 | KINOMEscan | Wild Type; Partial length | |||
| 200029 | ACVR2A | 200029 | P27037 | Activin A receptor, type IIA; ActR2; ACTRII; ACVR2; ACVR2A | KINOMEscan | Wild Type; Partial length | |||
| 200030 | ACVR2B | 200030 | Q13705 | Activin A receptor, type IIB; ActR2B; ACTRIIB; ActR-IIB; ACVR2B; MGC116908 | KINOMEscan | Wild Type; Partial length | |||
| 200031 | ACVRL1 | 200031 | P37023 | Activin A receptor type II-like 1; ACVRL1; ACVRLK1; ALK1; ALK-1; HHT; HHT2; ORW2; SKR3; TSR-I | KINOMEscan | Wild Type; Partial length | |||
| 200032 | ADCK3 | 200032 | Q8NI60 | Chaperone, ABC1 activity of bc1 complex homolog (S. pombe); ADCK3; ARCA2; CABC1; COQ8; MGC4849; SCAR9 | KINOMEscan | Wild Type; Full length | |||
| 200033 | ADCK4 | 200033 | Q96D53 | AarF domain containing kinase 4; ADCK4; FLJ12229 | KINOMEscan | Wild Type; Full length | |||
| 200034 | AKT1 | 200034 | P31749 | V-akt murine thymoma viral oncogene homolog 1; AKT; AKT1; Akt1/PKBa; MGC99656; PKB; PKBa; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | KINOMEscan | Wild Type; Partial length |