Basal profile of receptor tyrosine kinase signaling network measured by ELISA - Dataset (ID:20137)
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Cell Line | ERK (pg/cell) | Akt (pg/cell) | ErbB1 (pg/cell) | ErbB2 (pg/cell) | ErbB3 (pg/cell) | ErbB4 (pg/cell) | InsR (pg/cell) | IGF1R (pg/cell) | IGF2R (pg/cell) | VEGFR1 (pg/cell) | VEGFR2 (pg/cell) | VEGFR3 (pg/cell) | PDGFRa (pg/cell) | PDGFRb (pg/cell) | c-Met (pg/cell) | c-Kit (pg/cell) | EphA2 (pg/cell) | Src (pg/cell) | TrkA (pg/cell) | FGFR1 (pg/cell) | FGFR2 (pg/cell) | FGFR3 (pg/cell) | FGFR4 (pg/cell) | EpCAM (pg/cell) | pERK RnD (a.u.) | pERK CST (a.u.) | pAkt (a.u.) | pErbB1 (a.u.) | pErbB2 (a.u.) | pErbB3 (a.u.) | pErbB4 (a.u.) | pInsR (a.u.) | pIGF1R (a.u.) | pIGF1R (Y1131) (a.u.) | pVEGFR1 (a.u.) | pVEGFR2 (a.u.) | pVEGFR3 (a.u.) | pPDGFRa (a.u.) | pPDGFRb (a.u.) | pc-Met (a.u.) | pc-Kit (a.u.) | pEphA2 (a.u.) | pSrc (a.u.) | pTrkA (a.u.) | ER | PR |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MCF7 | 0.001550 | 0.127939 | 0.011460 | 0.023167 | 0.039686 | 0.000015 | 0.006522 | 0.074180 | 0.021787 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000158 | 0.013895 | 0.123345 | 0.000002 | 0.262003 | 0.000002 | 0.000018 | 0.000001 | 0.707886 | 0.000027 | 0.000407 | 0.033586 | 0.000014 | 0.002229 | 0.000052 | 0.000027 | 0.043588 | 0.000037 | 0.193246 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000023 | 0.000116 | 0.003922 | 0.002145 |
HCC1937 | 0.001734 | 0.023106 | 0.126316 | 0.023936 | 0.002304 | 0.000015 | 0.002695 | 0.001929 | 0.009279 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.199776 | 0.000000 | 0.135122 | 0.133118 | 0.000002 | 0.225204 | 0.000308 | 0.000847 | 0.000001 | 0.524161 | 0.000027 | 0.002131 | 0.296125 | 0.005225 | 0.002229 | 0.000052 | 0.005032 | 0.029760 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000120 | 0.000116 | 0.000072 | 0.000120 |
HCC1954 | 0.001529 | 0.029251 | 0.062116 | 2.028436 | 0.016195 | 0.000015 | 0.000061 | 0.007680 | 0.016718 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.630281 | 0.000079 | 0.027379 | 0.205159 | 0.000002 | 0.233839 | 0.000002 | 0.000018 | 0.000001 | 0.351399 | 0.000212 | 0.000950 | 0.678940 | 0.267708 | 0.854272 | 0.016644 | 0.017337 | 0.022861 | 0.004967 | 0.020476 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.007201 | 0.001249 | 0.000210 | 0.000225 | 0.000116 | 0.000019 | 0.000072 |
HCC38 | 0.001650 | 0.030563 | 0.040007 | 0.041302 | 0.024356 | 0.000015 | 0.001698 | 0.013109 | 0.015090 | 0.000145 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.011841 | 0.002042 | 0.072876 | 0.280569 | 0.000002 | 0.260344 | 0.001299 | 0.000018 | 0.000001 | 0.763470 | 0.000257 | 0.000854 | 0.077133 | 0.008259 | 0.008386 | 0.000052 | 0.005543 | 0.001929 | 0.005388 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000137 | 0.000116 | 0.000053 | 0.000133 |
MDA-MB-175-VII | 0.001428 | 0.047847 | 0.007853 | 0.074796 | 0.009289 | 0.000015 | 0.000061 | 0.007339 | 0.012638 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000000 | 0.014355 | 0.340263 | 0.000002 | 0.243260 | 0.000002 | 0.000018 | 0.000001 | 0.044485 | 0.000851 | 0.008435 | 0.296530 | 0.000541 | 0.015937 | 0.009106 | 0.008008 | 0.006831 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000375 | 0.000116 | 0.000090 | 0.000047 |
MCF 10A | 0.000421 | 0.025576 | 0.132898 | 0.017434 | 0.001298 | 0.000015 | 0.000061 | 0.098369 | 0.025642 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.234945 | 0.000000 | 0.017445 | 0.342839 | 0.000002 | 0.157427 | 0.000002 | 0.000326 | 0.000001 | 0.009659 | 0.000027 | 0.000704 | 0.096342 | 0.020160 | 0.008104 | 0.000052 | 0.009461 | 0.034734 | 0.006760 | 0.035226 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000150 | 0.000116 | 0.000017 | 0.000054 |
MCF 10F | 0.000436 | 0.033675 | 0.028976 | 0.031429 | 0.006930 | 0.000015 | 0.001362 | 0.008063 | 0.009513 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000222 | 0.399719 | 0.000000 | 0.015706 | 0.111644 | 0.000002 | 0.119441 | 0.000002 | 0.000018 | 0.000001 | 0.173890 | 0.000124 | 0.000194 | 0.069248 | 0.013895 | 0.004678 | 0.000052 | 0.003885 | 0.051867 | 0.016088 | 0.077511 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000116 | 0.001249 | 0.000023 | 0.000092 | 0.000116 | 0.000019 | 0.000062 |
MCF12A | 0.000301 | 0.016529 | 0.189237 | 0.008829 | 0.001731 | 0.000015 | 0.000061 | 0.013479 | 0.009227 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.510546 | 0.000000 | 0.017256 | 0.092326 | 0.000002 | 0.100947 | 0.000002 | 0.000018 | 0.000001 | 0.058942 | 0.000027 | 0.000134 | 0.017063 | 0.195698 | 0.002618 | 0.000052 | 0.000724 | 0.015404 | 0.010887 | 0.050437 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.009245 | 0.001249 | 0.000110 | 0.000256 | 0.000116 | 0.000058 | 0.000021 |
MDA-MB-157 | 0.001092 | 0.054440 | 0.034858 | 0.006675 | 0.000070 | 0.000015 | 0.002708 | 0.001602 | 0.016440 | 0.000834 | 0.000001 | 0.000193 | 0.000320 | 0.110015 | 0.000084 | 0.008668 | 0.074062 | 0.088522 | 0.000002 | 0.158241 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000027 | 0.000868 | 0.008996 | 0.002269 | 0.002229 | 0.000052 | 0.001407 | 0.006897 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000058 | 0.000116 | 0.000019 | 0.000130 |
BT-20 | 0.000448 | 0.019443 | 0.425506 | 0.032790 | 0.007417 | 0.000015 | 0.000823 | 0.029500 | 0.003761 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.194375 | 0.000000 | 0.003806 | 0.656693 | 0.000002 | 0.132703 | 0.000002 | 0.000018 | 0.000001 | 0.337435 | 0.000112 | 0.000428 | 0.204619 | 0.194717 | 0.011525 | 0.000052 | 0.003270 | 0.005037 | 0.000037 | 0.009023 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.006500 | 0.001249 | 0.000023 | 0.000273 | 0.000116 | 0.000026 | 0.000062 |
UACC-812 | 0.002318 | 0.062712 | 0.003552 | 1.079578 | 0.011629 | 0.000015 | 0.000061 | 0.020988 | 0.030159 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.215155 | 0.000000 | 0.017181 | 1.395831 | 0.000002 | 0.292940 | 0.000132 | 0.000018 | 0.000001 | 0.268856 | 0.001274 | 0.006187 | 0.206463 | 0.016533 | 0.595025 | 0.000052 | 0.015995 | 0.000016 | 0.000037 | 0.109902 | 0.000037 | 0.000013 | 0.002079 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000628 | 0.000116 | 0.000341 | 0.000552 |
MDA-MB-436 | 0.000792 | 0.015135 | 0.029664 | 0.002771 | 0.000755 | 0.000015 | 0.000061 | 0.009875 | 0.043402 | 0.000434 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.261698 | 0.000000 | 0.074511 | 0.038248 | 0.000002 | 0.161437 | 0.000002 | 0.000018 | 0.000001 | 0.004527 | 0.000187 | 0.001376 | 0.289644 | 0.001623 | 0.002229 | 0.000052 | 0.000027 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000041 | 0.000116 | 0.000006 | 0.000046 |
CAMA-1 | 0.001036 | 0.016002 | 0.023685 | 0.063188 | 0.038498 | 0.002453 | 0.001774 | 0.005626 | 0.012643 | 0.000121 | 0.000001 | 0.000193 | 0.000178 | 0.000136 | 0.000084 | 0.000000 | 0.000750 | 0.057732 | 0.000002 | 0.126539 | 0.000002 | 0.000018 | 0.004167 | 0.073086 | 0.000027 | 0.000478 | 0.270453 | 0.000507 | 0.007421 | 0.000052 | 0.001415 | 0.019842 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000025 | 0.000116 | 0.001466 | 0.004511 |
HCC1395 | 0.000674 | 0.040023 | 0.039355 | 0.003057 | 0.000070 | 0.000015 | 0.000061 | 0.001431 | 0.011892 | 0.000371 | 0.000001 | 0.000193 | 0.000798 | 0.000006 | 0.029478 | 0.000000 | 0.015589 | 0.122642 | 0.000002 | 0.172335 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000027 | 0.001426 | 0.353474 | 0.002759 | 0.002229 | 0.000052 | 0.000683 | 0.007266 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000158 | 0.000116 | 0.000006 | 0.000057 |
HCC1428 | 0.001057 | 0.075777 | 0.039530 | 0.038714 | 0.033628 | 0.001203 | 0.000061 | 0.024890 | 0.019215 | 0.000421 | 0.000001 | 0.000193 | 0.000178 | 0.000266 | 0.000084 | 0.000000 | 0.000837 | 1.543919 | 0.000002 | 0.176235 | 0.000002 | 0.000018 | 0.005277 | 0.166874 | 0.000109 | 0.000209 | 0.003641 | 0.014974 | 0.002229 | 0.000052 | 0.004321 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.004061 | 0.000080 | 0.000009 | 0.000134 | 0.003332 | 0.001249 | 0.000023 | 0.002004 | 0.000116 | 0.002332 | 0.001020 |
HCC1569 | 0.001239 | 0.025774 | 0.008103 | 1.209554 | 0.023939 | 0.000015 | 0.000061 | 0.063655 | 0.021025 | 0.000193 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.042288 | 0.000000 | 0.011558 | 1.525413 | 0.000002 | 0.217837 | 0.000745 | 0.000988 | 0.000001 | 0.107529 | 0.000572 | 0.000384 | 0.376618 | 0.014228 | 0.468610 | 0.000647 | 0.003379 | 0.003545 | 0.005121 | 0.001832 | 0.000037 | 0.000013 | 0.000399 | 0.000009 | 0.000134 | 0.002549 | 0.001249 | 0.000023 | 0.000337 | 0.000116 | 0.000060 | 0.000253 |
HCC70 | 0.001861 | 0.030250 | 0.187019 | 0.018492 | 0.008284 | 0.000015 | 0.000061 | 0.006480 | 0.008221 | 0.000007 | 0.000001 | 0.000193 | 0.000510 | 0.000006 | 0.081869 | 0.005246 | 0.010598 | 0.079143 | 0.000002 | 0.127848 | 0.000002 | 0.000018 | 0.000001 | 0.241041 | 0.000422 | 0.000287 | 0.287724 | 0.077648 | 0.002229 | 0.000052 | 0.001546 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000088 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000041 | 0.000116 | 0.000015 | 0.000067 |
HCC202 | 0.002293 | 0.083788 | 0.066754 | 0.935180 | 0.020796 | 0.000015 | 0.007420 | 0.003045 | 0.013029 | 0.000474 | 0.000001 | 0.000193 | 0.000178 | 0.000346 | 0.000084 | 0.000000 | 0.037725 | 0.250326 | 0.000002 | 0.264042 | 0.004160 | 0.000355 | 0.000253 | 0.991954 | 0.000945 | 0.007669 | 0.437659 | 0.038539 | 0.193317 | 0.000052 | 0.009899 | 0.019944 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000188 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000134 | 0.000116 | 0.000077 | 0.000228 |
HCC1806 | 0.000318 | 0.011655 | 0.129893 | 0.013936 | 0.005507 | 0.000015 | 0.001566 | 0.005981 | 0.014474 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000155 | 0.265546 | 0.001230 | 0.040565 | 0.152646 | 0.000002 | 0.111444 | 0.000212 | 0.000517 | 0.000001 | 0.220721 | 0.000027 | 0.000424 | 0.006053 | 0.010389 | 0.004573 | 0.000052 | 0.001242 | 0.003796 | 0.001630 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000519 | 0.000134 | 0.002095 | 0.001249 | 0.000023 | 0.000077 | 0.000116 | 0.000029 | 0.000044 |
MDA-MB-231 | 0.000398 | 0.036028 | 0.083694 | 0.007956 | 0.000596 | 0.000015 | 0.000061 | 0.004737 | 0.031148 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.006061 | 0.080205 | 0.000000 | 0.117453 | 0.225337 | 0.000002 | 0.145332 | 0.000002 | 0.000018 | 0.000001 | 0.011123 | 0.000240 | 0.000712 | 0.006677 | 0.009967 | 0.003507 | 0.000052 | 0.001369 | 0.004480 | 0.000037 | 0.011474 | 0.000037 | 0.000013 | 0.000080 | 0.000578 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000116 | 0.000116 | 0.000025 | 0.000067 |
MDA-MB-361 | 0.001199 | 0.067506 | 0.001650 | 0.209101 | 0.014416 | 0.000015 | 0.003542 | 0.015756 | 0.016276 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000000 | 0.001031 | 0.100950 | 0.000002 | 0.126329 | 0.001094 | 0.000018 | 0.000001 | 0.283766 | 0.000027 | 0.000755 | 0.056652 | 0.005513 | 0.076155 | 0.000052 | 0.000802 | 0.014004 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000705 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000106 | 0.000116 | 0.001168 | 0.001303 |
ZR-75-30 | 0.000961 | 0.079347 | 0.000084 | 2.054386 | 0.048846 | 0.000015 | 0.000061 | 0.007411 | 0.017689 | 0.000007 | 0.000001 | 0.000193 | 0.000605 | 0.000006 | 0.000084 | 0.000000 | 0.003164 | 0.221002 | 0.000002 | 0.194097 | 0.000002 | 0.001923 | 0.000145 | 0.057962 | 0.002051 | 0.004394 | 0.348622 | 0.002119 | 0.992071 | 0.020984 | 0.010718 | 0.022800 | 0.006964 | 0.001832 | 0.000037 | 0.000013 | 0.002139 | 0.001049 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000072 | 0.000116 | 0.000927 | 0.000116 |
HCC1187 | 0.001231 | 0.067625 | 0.078729 | 0.041583 | 0.003479 | 0.000015 | 0.011093 | 0.000584 | 0.052908 | 0.000770 | 0.001859 | 0.000193 | 0.000393 | 0.000289 | 0.000084 | 0.018901 | 0.003747 | 0.287014 | 0.000002 | 0.279688 | 0.000459 | 0.000018 | 0.000001 | 0.158536 | 0.000156 | 0.000638 | 0.249109 | 0.010311 | 0.015487 | 0.000052 | 0.001503 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.011705 | 0.000080 | 0.001174 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000065 | 0.000116 | 0.000059 | 0.000147 |
T47D | 0.000537 | 0.031946 | 0.009859 | 0.035689 | 0.027587 | 0.000443 | 0.002633 | 0.023322 | 0.017964 | 0.000220 | 0.000001 | 0.000193 | 0.000178 | 0.000267 | 0.000084 | 0.000000 | 0.001839 | 0.284085 | 0.000002 | 0.196300 | 0.001170 | 0.000018 | 0.000001 | 0.166496 | 0.000225 | 0.000704 | 0.184693 | 0.003680 | 0.011140 | 0.000052 | 0.004440 | 0.005092 | 0.006041 | 0.026736 | 0.000037 | 0.000013 | 0.000080 | 0.001178 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000127 | 0.000116 | 0.001290 | 0.019619 |
184B5 | 0.000454 | 0.014484 | 0.199552 | 0.017611 | 0.002111 | 0.000015 | 0.001482 | 0.024421 | 0.024712 | 0.000108 | 0.001064 | 0.000193 | 0.000341 | 0.000006 | 0.421684 | 0.000000 | 0.022577 | 0.728929 | 0.000002 | 0.131405 | 0.000002 | 0.000018 | 0.000001 | 0.043860 | 0.000121 | 0.000989 | 0.064621 | 0.073694 | 0.004421 | 0.000052 | 0.001946 | 0.075541 | 0.018317 | 0.028019 | 0.000037 | 0.000013 | 0.000080 | 0.001258 | 0.000134 | 0.000879 | 0.001249 | 0.000023 | 0.000471 | 0.000430 | 0.000013 | 0.000061 |