Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Vorinostat | BT-549 | -1.7282 | 0.9763 | -3.7867 | -3.7732 | -3.8441 | 1.6545 | 0.0265 | 0.0271 | 5.8501 |
| Vorinostat | CAMA-1 | -1.7282 | 0.9860 | -3.9737 | -3.9427 | -4.1599 | 2.4790 | 0.0859 | 0.0859 | 5.5144 |
| Vorinostat | HCC1143 | -1.7282 | 0.9834 | -3.8282 | -3.7422 | -3.9269 | 1.4220 | 0.1231 | 0.1240 | 5.9119 |
| Vorinostat | HCC1395 | -1.7282 | 0.9685 | -3.2412 | -3.1662 | -3.5329 | 1.3890 | 0.1061 | 0.1132 | 6.5976 |
| Vorinostat | HCC1419 | -1.7282 | 0.9819 | -3.4097 | -3.3978 | -4.0907 | 1.4830 | 0.0170 | 0.0191 | 5.9465 |
| Vorinostat | HCC1428 | -1.7282 | 0.9949 | -4.2092 | -4.2032 | -4.4423 | 2.2960 | 0.0140 | 0.0140 | 5.0661 |
| Vorinostat | HCC1569 | -1.7282 | 0.9773 | -3.9042 | -3.8723 | -4.0163 | 1.2645 | 0.0441 | 0.0460 | 5.5184 |
| Vorinostat | HCC1806 | -1.7282 | 0.9701 | -3.7827 | -3.7802 | -3.9185 | 1.3230 | 0.0040 | 0.0060 | 5.4870 |
| Vorinostat | HCC1937 | -1.7282 | 0.9718 | -3.6102 | -3.4912 | -3.7892 | 1.0650 | 0.1263 | 0.1349 | 6.2378 |
| Vorinostat | HCC1954 | -1.7282 | 0.9731 | -3.7032 | -3.7033 | -4.0119 | 0.8718 | 0.0000 | 0.0265 | 5.5986 |
| Vorinostat | HCC202 | -1.7282 | 0.9908 | -4.3372 | -4.3324 | -4.7003 | 2.1110 | 0.0108 | 0.0108 | 4.8313 |
| Vorinostat | HCC38 | -1.7282 | 0.9825 | -4.3132 | -4.3087 | -4.5043 | 1.6240 | 0.0083 | 0.0084 | 4.6555 |
| Vorinostat | HCC70 | -1.7282 | 0.9938 | -4.1322 | -4.1327 | -4.4808 | 1.3560 | 0.0000 | 0.0005 | 5.0455 |
| Vorinostat | Hs 578T | -1.7282 | 0.9410 | -3.6062 | -3.5936 | -3.6502 | 1.9030 | 0.0184 | 0.0189 | 5.9870 |
| Vorinostat | MB 157 | -1.7282 | 0.9916 | -3.9622 | -3.9617 | -4.1528 | 0.9727 | 0.0000 | 0.0067 | 5.2394 |
| Vorinostat | MDA-MB-134-VI | -1.7282 | 0.9644 | -4.0162 | -3.7735 | -4.4372 | 1.1614 | 0.2381 | 0.2410 | 6.0621 |
| Vorinostat | MDA-MB-157 | -1.7282 | 0.9836 | -3.6842 | -3.6807 | -4.0301 | 1.0980 | 0.0005 | 0.0081 | 5.6000 |
| Vorinostat | MDA-MB-175-VII | -1.7282 | 0.9681 | -3.4972 | -3.4671 | -4.2736 | 0.8134 | 0.0279 | 0.0639 | 5.9314 |
| Vorinostat | MDA-MB-361 | -1.7282 | 0.9885 | -3.9522 | -3.9523 | -4.2812 | 1.5620 | 0.0002 | 0.0007 | 5.1490 |
| Vorinostat | MDA-MB-436 | -1.7282 | 0.9632 | -3.6972 | -3.4722 | -3.8559 | 0.6621 | 0.1454 | 0.1858 | 6.0759 |
| Vorinostat | MDA-MB-453 | -1.7282 | 0.9840 | -4.3772 | -4.3740 | -4.5085 | 2.6485 | 0.0172 | 0.0172 | 4.5390 |
| Vorinostat | MDA-MB-468 | -1.7282 | 0.9866 | -3.6302 | -3.6226 | -3.7358 | 1.8625 | 0.0163 | 0.0176 | 5.7913 |
| Vorinostat | T47D | -1.7282 | 0.9900 | -3.8622 | -3.8592 | -4.0327 | 2.4345 | 0.0096 | 0.0097 | 5.4004 |
| Vorinostat | UACC-812 | -1.7282 | 0.8915 | -3.6012 | -3.5701 | -4.5439 | 0.6830 | 0.0268 | 0.0787 | 5.6651 |
| Vorinostat | UACC-893 | -1.7282 | 0.9833 | -4.0442 | -4.0369 | -4.3752 | 1.6240 | 0.0143 | 0.0145 | 5.1473 |