Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Ixabepilone | MDA-MB-453 | -4.4045 | 0.7898 | -8.5530 | -8.3732 | -8.5682 | 2.5575 | 0.3220 | 0.3220 | 5.1848 |
| Ixabepilone | MDA-MB-468 | -4.4045 | 0.9778 | -8.3945 | -8.3616 | -8.4847 | 1.5860 | 0.0568 | 0.0568 | 3.1497 |
| Ixabepilone | T47D | -4.4045 | 0.9194 | -7.7495 | -7.5412 | -7.8976 | 1.3420 | 0.2373 | 0.2373 | 5.1704 |
| Ixabepilone | UACC-812 | -4.4045 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 6.3108 |
| Ixabepilone | UACC-893 | -4.4045 | 0.8369 | -7.8275 | -7.5910 | -8.0985 | 1.5765 | 0.2849 | 0.2849 | 5.1106 |
| Ixabepilone | ZR-75-1 | -4.4045 | 0.9781 | -6.1175 | -6.1170 | -6.3495 | 1.8750 | 0.0018 | 0.0024 | 6.0236 |
| Ixabepilone | 184B5 | -4.4045 | 0.9619 | -6.4745 | -6.4747 | -7.0501 | 0.6073 | 0.0000 | 0.0553 | 5.4131 |
| Ixabepilone | HCC1187 | -4.4045 | 0.9872 | -8.6105 | -8.6026 | -8.7327 | 3.2200 | 0.0327 | 0.0327 | 2.8018 |
| Ixabepilone | MCF 10A | -4.4045 | 0.9429 | -8.0355 | -8.0110 | -8.0613 | 2.5570 | 0.0488 | 0.0488 | 3.8590 |
| Ixabepilone | MCF 10F | -4.4045 | 0.8943 | -6.9115 | -6.9112 | -8.0650 | 0.4363 | 0.0000 | 0.0746 | 4.8821 |
| Ixabepilone | SUM1315MO2 | -4.4045 | 0.8868 | -7.9425 | -7.7389 | -8.2229 | 1.6960 | 0.2605 | 0.2605 | 4.5519 |
| Ixabepilone | SUM149PT | -4.4045 | 0.9637 | -8.2275 | -8.1536 | -8.3009 | 1.3730 | 0.1035 | 0.1035 | 3.6488 |
| Ixabepilone | SUM159PT | -4.4045 | 0.9785 | -8.1955 | -8.1674 | -8.2110 | 1.8280 | 0.0548 | 0.0548 | 3.3677 |
| Ixabepilone | SUM185PE | -4.4045 | 0.8184 | -6.3905 | -6.3904 | NaN | 0.3353 | 0.0000 | 0.1775 | 5.2632 |
| Ixabepilone | SUM225CWN | -4.4045 | 0.7880 | -6.3655 | -6.3658 | -7.3405 | 0.3496 | 0.0000 | 0.1730 | 5.4720 |
| Ixabepilone | SUM229PE | -4.4045 | 0.9201 | -8.2320 | -8.1023 | -8.6795 | 0.8597 | 0.1193 | 0.1255 | 3.9019 |
| Ixabepilone | SUM52PE | -4.4045 | 0.8127 | -8.4715 | -8.2024 | -8.8825 | 0.8237 | 0.1911 | 0.2049 | 4.0147 |
| Ixabepilone | 184A1 | -4.4045 | 0.9686 | -6.3850 | -6.3849 | -6.7272 | 1.6995 | 0.0010 | 0.0343 | 5.5116 |
| Ixabepilone | MCF12A | -4.4045 | 0.9854 | -8.0605 | -8.0065 | -8.1636 | 0.8859 | 0.0525 | 0.0530 | 3.5632 |
| Ixabepilone | MX1 | -4.4045 | 0.8381 | -7.1345 | -6.8647 | -8.5408 | 0.3549 | 0.0989 | 0.1863 | 5.0933 |
| Ixabepilone | T47DKBLUC | -4.4045 | 0.7124 | -7.7555 | -7.0138 | -8.0200 | 0.7261 | 0.3552 | 0.3576 | 5.8298 |
| Ixabepilone | 600MPE | -4.4045 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 6.6783 |
| Ixabepilone | HCC2185 | -4.4045 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 6.5816 |
| Ixabepilone | HCC3153 | -4.4045 | 0.9494 | -8.0295 | -7.8600 | -8.2162 | 1.7260 | 0.1971 | 0.1971 | 4.3942 |
| Ixabepilone | LY2 | -4.4045 | 0.9574 | -8.1385 | -8.0814 | -8.2570 | 2.0620 | 0.1187 | 0.1187 | 3.9722 |