NVP-BHG712 KiNativ -- multiple dose experiment - Dataset (ID:20104)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| NVP-BHG712 | PC-3 | IRAK4 | DIkSANILLDEAFTAK | Lys2 | 10.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | IRE1 | DLkPHNILISMPNAHGK | Lys2 | 12.9 | 5.00 | uM |
| NVP-BHG712 | PC-3 | ITPK1 | ESIFFNSHNVSkPESSSVLTELDKIEGVFERPSDEVIR | ATP | -8.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | JAK1 | QLASALSYLEDKDLVHGNVCTkNLLLAR | Other | -27.5 | 5.00 | uM |
| NVP-BHG712 | PC-3 | JAK1_domain2 | IGDFGLTkAIETDKEYYTVK | Activation Loop | 50.7 | 5.00 | uM |
| NVP-BHG712 | PC-3 | JAK1 domain2 | IGDFGLTkAIETDKEYYTVKDDR | Activation Loop | 39.5 | 5.00 | uM |
| NVP-BHG712 | PC-3 | JNK1,JNK2,JNK3 | DLkPSNIVVK | Lys2 | 9.3 | 5.00 | uM |
| NVP-BHG712 | PC-3 | KHS1 | NVHTGELAAVkIIK | Lys1 | 1.3 | 5.00 | uM |
| NVP-BHG712 | PC-3 | M4K3 | NVNTGELAAIkVIK | Lys1 | 4.6 | 5.00 | uM |
| NVP-BHG712 | PC-3 | LATS1 | ALYATkTLR | Lys1 | 5.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | LATS2 | DIkPDNILIDLDGHIK | Lys2 | -33.0 | 5.00 | uM |
| NVP-BHG712 | PC-3 | LKB1 | DIkPGNLLLTTGGTLK | Lys2 | 9.5 | 5.00 | uM |
| NVP-BHG712 | PC-3 | LOK | NKETGALAAAkVIETK | Lys1 | 2.7 | 5.00 | uM |
| NVP-BHG712 | PC-3 | LOK | DLkAGNVLMTLEGDIR | Lys2 | 26.7 | 5.00 | uM |
| NVP-BHG712 | PC-3 | MAP2K1,MAP2K2 | DVkPSNILVNSR | Lys2 | 11.9 | 5.00 | uM |
| NVP-BHG712 | PC-3 | MAP2K3 | MCDFGISGYLVDSVAkTMDAGCKPYMAPER | Activation Loop | 37.8 | 5.00 | uM |
| NVP-BHG712 | PC-3 | MAP2K3 | DVkPSNVLINK | Lys2 | 19.5 | 5.00 | uM |
| NVP-BHG712 | PC-3 | MAP2K4 | LCDFGISGQLVDSIAkTR | Activation Loop | -2.8 | 5.00 | uM |
| NVP-BHG712 | PC-3 | MAP2K4 | DIkPSNILLDR | Lys2 | 13.5 | 5.00 | uM |
| NVP-BHG712 | PC-3 | MAP2K5 | DVkPSNMLVNTR | Lys2 | 6.0 | 5.00 | uM |
| NVP-BHG712 | PC-3 | MAP2K6 | HVPSGQIMAVkR | Lys1 | 14.4 | 5.00 | uM |
| NVP-BHG712 | PC-3 | MAP2K6 | DVkPSNVLINALGQVK | Lys2 | 6.8 | 5.00 | uM |
| NVP-BHG712 | PC-3 | M3K2 | VYLCYDVDTGRELAVkQVQFDPDSPETSKEVNALECEIQLLK | Lys1 | -26.8 | 5.00 | uM |
| NVP-BHG712 | PC-3 | M3K2 | ELAVkQVQFDPDSPETSKEVNALECEIQLLK | Lys1 | -10.5 | 5.00 | uM |
| NVP-BHG712 | PC-3 | M3K2,MAP3K3 | DIkGANILR | Lys2 | 12.9 | 5.00 | uM |