NVP-BHG712 KiNativ -- multiple dose experiment - Dataset (ID:20104)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| NVP-BHG712 | PC-3 | EPHB2 | FLEDDTSDPTYTSALGGkIPIR | Activation Loop | 92.0 | 5.00 | uM |
| NVP-BHG712 | PC-3 | EPHB4 | FLEENSSDPTYTSSLGGkIPIR | Activation Loop | 96.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | MK03 | YIHSANVLHRDLkPSNLLINTTCDLK | Lys2 | 2.3 | 5.00 | uM |
| NVP-BHG712 | PC-3 | MK03 | DLkPSNLLINTTCDLK | Lys2 | 6.7 | 5.00 | uM |
| NVP-BHG712 | PC-3 | MK01 | YIHSANVLHRDLkPSNLLLNTTCDLK | Lys2 | -11.5 | 5.00 | uM |
| NVP-BHG712 | PC-3 | Erk5 | DLkPSNLLVNENCELK | Lys2 | 6.8 | 5.00 | uM |
| NVP-BHG712 | PC-3 | FAK | CIGEGQFGDVHQGIYMSPENPALAVAIkTCK | Lys1 | 23.8 | 5.00 | uM |
| NVP-BHG712 | PC-3 | FER | QEDGGVYSSSGLkQIPIK | Activation Loop | 10.8 | 5.00 | uM |
| NVP-BHG712 | PC-3 | FER | TSVAVkTCKEDLPQELK | Lys1 | -4.6 | 5.00 | uM |
| NVP-BHG712 | PC-3 | FRAP1 | IQSIAPSLQVITSkQRPR | ATP | 1.3 | 5.00 | uM |
| NVP-BHG712 | PC-3 | FYN,SRC,YES | QGAkFPIKWTAPEAALYGR | Activation Loop | 51.4 | 5.00 | uM |
| NVP-BHG712 | PC-3 | GCK | DTVTSELAAVkIVK | Lys1 | 21.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | GCK | DIkGANLLLTLQGDVK | Lys2 | 9.4 | 5.00 | uM |
| NVP-BHG712 | PC-3 | GCN2_domain2 | VQNKLDGCCYAVkR | Lys1 | 11.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | GCN2 | LDGCCYAVkR | Lys1 | 15.3 | 5.00 | uM |
| NVP-BHG712 | PC-3 | GCN2_domain2 | DLkPVNIFLDSDDHVK | Lys2 | -3.2 | 5.00 | uM |
| NVP-BHG712 | PC-3 | GSK3A | DIkPQNLLVDPDTAVLK | Lys2 | 6.7 | 5.00 | uM |
| NVP-BHG712 | PC-3 | GSK3B | DIkPQNLLLDPDTAVLK | Lys2 | 1.7 | 5.00 | uM |
| NVP-BHG712 | PC-3 | ERBB2 | GIWIPDGENVKIPVAIkVLR | Lys1 | -14.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | IKKA | DLkPENIVLQDVGGK | Lys2 | 12.3 | 5.00 | uM |
| NVP-BHG712 | PC-3 | IKKB | DLkPENIVLQQGEQR | Lys2 | 20.5 | 5.00 | uM |
| NVP-BHG712 | PC-3 | IKKE,TBK1 | DIkPGNIMR | Lys2 | 16.2 | 5.00 | uM |
| NVP-BHG712 | PC-3 | ILK | WQGNDIVVkVLK | Lys1 | 13.9 | 5.00 | uM |
| NVP-BHG712 | PC-3 | ILK | ISMADVkFSFQCPGR | Protein Kinase Domain | 26.4 | 5.00 | uM |
| NVP-BHG712 | PC-3 | IRAK1 | AIQFLHQDSPSLIHGDIkSSNVLLDER | Lys2 | 3.0 | 5.00 | uM |