XMD8-92 KiNativ -- single dose experiment - Dataset (ID:20102)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
XMD8-92 HeLa PI42C
TLVIkEVSSEDIADMHSNLSNYHQYIVK
ATP
3.6
 10
uM
XMD8-92 PC-3 CaMK2g
TSTQEYAAkIINTK
Lys1
7.2
 10
uM
XMD8-92 HeLa CaMK2g
TSTQEYAAkIINTK
Lys1
2.7
 10
uM
XMD8-92 PC-3 FER
TSVAVkTCKEDLPQELK
Lys1
5.2
 10
uM
XMD8-92 HeLa FER
TSVAVkTCKEDLPQELK
Lys1
-2.2
 10
uM
XMD8-92 HeLa ACK
TVSVAVkCLKPDVLSQPEAMDDFIR
Lys1
40.4
 10
uM
XMD8-92 PC-3 CHK2
VAIkIISK
Lys1
2.6
 10
uM
XMD8-92 PC-3 SRC
VAIkTLKPGTMSPEAFLQEAQVMK
Lys1
17.5
 10
uM
XMD8-92 PC-3 AMPKa1,AMPKa2
VAVkILNR
Lys1
3.9
 10
uM
XMD8-92 HeLa AMPKa1,AMPKa2
VAVkILNR
Lys1
6.7
 10
uM
XMD8-92 HeLa LYN
VAVkTLKPGTMSVQAFLEEANLMK
Lys1
-6.0
 10
uM
XMD8-92 HeLa LATS2
VDTHALYAMkTLR
Lys1
-11.5
 10
uM
XMD8-92 PC-3 PIK3CB
VFGEDSVGVIFkNGDDLRQDMLTLQMLR
ATP
-69.6
 10
uM
XMD8-92 PC-3 EphA7
VIEDDPEAVYTTTGGkIPVR
Activation Loop
-5.7
 10
uM
XMD8-92 PC-3 EPHA2
VLEDDPEATYTTSGGkIPIR
Activation Loop
-2.0
 10
uM
XMD8-92 HeLa RSK1,RSK4 domain1
VLGQGSFGkVFLVR
ATP Loop
11.1
 10
uM
XMD8-92 HeLa MSK1,MSK2_domain1
VLGTGAYGkVFLVR
ATP Loop
-4.9
 10
uM
XMD8-92 HeLa RSKL1_domain1
VLGVIDkVLLVMDTR
Protein Kinase Domain
-20.2
 10
uM
XMD8-92 HeLa PAN3
VMDPTkILITGK
-4.5
 10
uM
XMD8-92 HeLa PI4KB
VPHTQAVVLNSkDK
ATP
14.2
 10
uM
XMD8-92 PC-3 PI4KB
VPHTQAVVLNSkDK
ATP
7.0
 10
uM
XMD8-92 HeLa CSK
VSDFGLTkEASSTQDTGKLPVK
Activation Loop
-7.0
 10
uM
XMD8-92 PC-3 CSK
VSDFGLTkEASSTQDTGKLPVK
Activation Loop
-16.1
 10
uM
XMD8-92 PC-3 M3K2
VYLCYDVDTGRELAVkQVQFDPDSPETSKEVNALECEIQLLK
Lys1
-3.4
 10
uM
XMD8-92 PC-3 MLTK
WISQDKEVAVKk
Lys1
10.9
 10
uM