XMD8-92 KiNativ -- single dose experiment - Dataset (ID:20102)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
XMD8-92 PC-3 ROCK1,ROCK2
DVkPDNMLLDK
Lys2
-11.0
 10
uM
XMD8-92 PC-3 RON
IQCAIkSLSR
Lys1
-5.6
 10
uM
XMD8-92 HeLa RSK1 domain1
LTDFGLSkEAIDHEK
Activation Loop
-25.7
 10
uM
XMD8-92 HeLa RSK1,RSK2_domain1
DLkPENILLDEEGHIKLTDFGLSK
Lys2
30.3
 10
uM
XMD8-92 HeLa RSK1,RSK4 domain1
VLGQGSFGkVFLVR
ATP Loop
11.1
 10
uM
XMD8-92 HeLa RSK2_domain1
LTDFGLSkESIDHEKK
Activation Loop
-2.5
 10
uM
XMD8-92 PC-3 RSK2_domain2
SkRDPTEEIEILLR
Protein Kinase Domain
22.4
 10
uM
XMD8-92 HeLa RSK2_domain2
SkRDPTEEIEILLR
Protein Kinase Domain
-9.2
 10
uM
XMD8-92 PC-3 RSK2_domain2
DLkPSNILYVDESGNPESIR
Lys2
27.9
 10
uM
XMD8-92 HeLa RSKL1_domain1
VLGVIDkVLLVMDTR
Protein Kinase Domain
-20.2
 10
uM
XMD8-92 HeLa SGK3
FYAVkVLQK
Lys1
-8.8
 10
uM
XMD8-92 HeLa SLK
DLkAGNILFTLDGDIK
Lys2
-6.5
 10
uM
XMD8-92 PC-3 SLK
ETSVLAAAkVIDTK
Lys1
-9.3
 10
uM
XMD8-92 PC-3 SLK
DLkAGNILFTLDGDIK
Lys2
4.3
 10
uM
XMD8-92 HeLa SMG1
DTVTIHSVGGTITILPTkTKPK
ATP
6.4
 10
uM
XMD8-92 PC-3 SNRK
DLkPENVVFFEK
Lys2
0.3
 10
uM
XMD8-92 PC-3 SRC
VAIkTLKPGTMSPEAFLQEAQVMK
Lys1
17.5
 10
uM
XMD8-92 PC-3 SRPK1
IIHTDIkPENILLSVNEQYIR
Lys2
6.6
 10
uM
XMD8-92 PC-3 SRPK1/2
FVAMkVVK
Lys1
-17.9
 10
uM
XMD8-92 HeLa STLK5
YSVkVLPWLSPEVLQQNLQGYDAK
Activation Loop
-20.9
 10
uM
XMD8-92 HeLa SYK
ISDFGLSkALR
Activation Loop
-2.7
 10
uM
XMD8-92 PC-3 TAO1,TAOK3
DIkAGNILLTEPGQVK
Lys2
5.6
 10
uM
XMD8-92 HeLa TAO1,TAOK3
DIkAGNILLTEPGQVK
Lys2
-28.1
 10
uM
XMD8-92 PC-3 TAOK2
DVkAGNILLSEPGLVK
Lys2
5.6
 10
uM
XMD8-92 HeLa TBK1
TGDLFAIkVFNNISFLRPVDVQMR
Lys1
-43.4
 10
uM