PLX-4720 KiNativ -- dose response experiment - Dataset (ID:20090)
Proteins Studied
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LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
---|---|---|---|---|---|---|---|---|---|
200711 | LATS1 | 200711 | O95835 | Serine/threonine-protein kinase LATS1 | KiNativ | ||||
200666 | CHK2 | 200666 | O96017 | Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog | KiNativ | ||||
200634 | ABL,ARG | 200634 | P00519 | Proto-oncogene tyrosine-protein kinase ABL1 | KiNativ | ||||
200633 | ABL,ARG | 200633 | P00519 | Proto-oncogene tyrosine-protein kinase ABL1 | KiNativ | ||||
200678 | EGFR | 200678 | P00533 | Epidermal growth factor receptor precursor | KiNativ | ||||
200813 | RAF1 | 200813 | P04049 | RAF proto-oncogene serine/threonine-protein kinase; CRAF; c-Raf; NS5; RAF1; Raf-1 | KiNativ | ||||
200687 | FYN,SRC,YES | 200687 | P06241 | Proto-oncogene tyrosine-protein kinase Fyn | KiNativ | ||||
200654 | CDC2 | 200654 | P06493 | Cell division control protein 2 homolog | KiNativ | ||||
200641 | ARAF | 200641 | P10398 | A-Raf proto-oncogene serine/threonine-protein kinase | KiNativ | ||||
200659 | CDK4 | 200659 | P11802 | Cyclin-dependent kinase 4; cell division protein kinase 4 | KiNativ | ||||
200831 | SRC | 200831 | P12931 | Proto-oncogene tyrosine-protein kinase Src; V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); ASV; c-SRC; p60-Src; SRC; SRC1 | KiNativ | ||||
200832 | SRC | 200832 | P12931 | Proto-oncogene tyrosine-protein kinase Src; V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); ASV; c-SRC; p60-Src; SRC; SRC1 | KiNativ | ||||
200647 | BRAF | 200647 | P15056 | Serine/threonine-protein kinase B-raf; v-raf murine sarcoma viral oncogene homolog B1; BRAF1; RAFB1 | KiNativ | ||||
200788 | PHKg2 | 200788 | P15735 | Phosphorylase b kinase gamma catalytic chain, testis/liver isoform | KiNativ | ||||
200685 | FER | 200685 | P16591 | Proto-oncogene tyrosine-protein kinase FER | KiNativ | ||||
200684 | FER | 200684 | P16591 | Proto-oncogene tyrosine-protein kinase FER | KiNativ | ||||
200686 | FER | 200686 | P16591 | Proto-oncogene tyrosine-protein kinase FER | KiNativ | ||||
200802 | PKCa,PKCb | 200802 | P17252 | Protein kinase C alpha type | KiNativ | ||||
200809 | PKR | 200809 | P19525 | Interferon-induced, double-stranded RNA-activated protein kinase | KiNativ | ||||
200801 | PITSLRE | 200801 | P21127 | PITSLRE serine/threonine-protein kinase CDC2L1 | KiNativ | ||||
200811 | PRKACB | 200811 | P22694 | CAMP-dependent protein kinase catalytic subunit beta | KiNativ | ||||
200778 | KS6B1 | 200778 | P23443 | Ribosomal protein S6 kinase 1 (EC 2.7.1.37) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) | KiNativ | ||||
200780 | p70S6K,p70S6Kb | 200780 | P23443 | Ribosomal protein S6 kinase 1 (EC 2.7.1.37) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) | KiNativ | ||||
200779 | KS6B1 | 200779 | P23443 | Ribosomal protein S6 kinase 1 (EC 2.7.1.37) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) | KiNativ | ||||
200704 | JAK1 | 200704 | P23458 | Tyrosine-protein kinase JAK1 | KiNativ |