SGI-1776 - Small Molecule (ID:10288-101)

HMS LINCS ID: 10288-101
Name: SGI-1776
Alternative Names:
LINCS ID: LSM-6307
PubChem CID: 24795070
ChEBI ID:
ChEMBL ID:
Molecular Mass: 405.18
InChi: InChI=1S/C20H22F3N5O/c1-27-9-7-14(8-10-27)12-24-18-5-6-19-25-13-17(28(19)26-18)15-3-2-4-16(11-15)29-20(21,22)23/h2-6,11,13-14H,7-10,12H2,1H3,(H,24,26)
InChi Key: MHXGEROHKGDZGO-UHFFFAOYSA-N
SMILES: CN1CCC(CC1)CNC2=NN3C(=NC=C3C4=CC(=CC=C4)OC(F)(F)F)C=C2
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
FLT3, GSG2, PIM1, PIM3
2
(equivalent to 100 nM ≤ Kd < 1µM)
KCNH2, PIM2
3
(equivalent to 1µM ≤ Kd < 10 µM)
YES1

Batch Information for HMSL10288-101-1:

HMS LINCS Batch ID: 10288-101-1
Provider: Selleck Chemicals
Provider Batch ID: S219802
Salt: 101
Molecular Formula: C20H22F3N5O
Molecular Weight: 405.42
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2013-03-04
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10288-101-1:

Date HMS QC Outcome Comment Files
04/13/2015 PASS HMSL10288-101-1_NMR.pdf,
HMSL10288-101-1_LCMS.pdf