Proteins

LINCS ID Name HMS LINCS ID UniProt ID Alternative Names Provider Mutation Phosphlorylation State Domain Protein Description
200515 FLT3 200515 P36888
Receptor-type tyrosine-protein kinase FLT3; fms-related tyrosine kinase 3
200514 FGFR1 200514 P11362
Fibroblast growth factor receptor 1
200513 FAK 200513 Q05397
Focal adhesion kinase 1; PTK2 protein tyrosine kinase 2
200543 p53 200543 P04637
Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
200512 ERK5 200512 Q13164
Mitogen-activated protein kinase 7
200511 ERK-2 200511 P28482
Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2
200510 ERK-1 200510 P27361
Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1
200547 PDK1 200547 O15530
3-phosphoinositide-dependent protein kinase 1
200509 erbB-2 200509 P04626
Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD340
200508 EPHB3 200508 P54753
Ephrin type-B receptor 3; EPHB3; ETK2; HEK2; TYRO6
200507 EGFR 200507 P00533
Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
200506 DNA-PK 200506 P78527
DNA-dependent protein kinase catalytic subunit
200505 DDR1 200505 Q08345
Epithelial discoidin domain-containing receptor 1; discoidin domain receptor tyrosine kinase 1
200504 CSF1R 200504 P07333
Macrophage colony-stimulating factor 1 receptor; colony stimulating factor 1 receptor
200503 c-Raf 200503 P04049
RAF proto-oncogene serine/threonine-protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
200555 Src 200555 P12931
Proto-oncogene tyrosine-protein kinase Src; V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); ASV; c-SRC; p60-Src; SRC; SRC1
200502 c-Met 200502 P08581
Hepatocyte growth factor receptor; met proto-oncogene (hepatocyte growth factor receptor)
200501 c-Kit 200501 P10721
Mast/stem cell growth factor receptor Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
200500 CHK2 200500 O96017
Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog
200559 1433G 200559 P61981
14-3-3 protein gamma
200560 ABL(T315I) 200560 T315I
200014 ABL1(M351T) 200014 P00519
C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl
KINOMEscan M351T
200002 ABL1 200002 P00519
C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl
KINOMEscan
201419 PIK3CA(H1047R) 201419 P42336
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha
KINOMEscan H1047R
200564 TGFR1 200564 P36897
TGF-beta receptor type-1; ALK5