Proteins
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LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
---|---|---|---|---|---|---|---|---|---|
200515 | FLT3 | 200515 | P36888 | Receptor-type tyrosine-protein kinase FLT3; fms-related tyrosine kinase 3 | |||||
200514 | FGFR1 | 200514 | P11362 | Fibroblast growth factor receptor 1 | |||||
200513 | FAK | 200513 | Q05397 | Focal adhesion kinase 1; PTK2 protein tyrosine kinase 2 | |||||
200543 | p53 | 200543 | P04637 | Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53 | |||||
200512 | ERK5 | 200512 | Q13164 | Mitogen-activated protein kinase 7 | |||||
200511 | ERK-2 | 200511 | P28482 | Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2 | |||||
200510 | ERK-1 | 200510 | P27361 | Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1 | |||||
200547 | PDK1 | 200547 | O15530 | 3-phosphoinositide-dependent protein kinase 1 | |||||
200509 | erbB-2 | 200509 | P04626 | Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD340 | |||||
200508 | EPHB3 | 200508 | P54753 | Ephrin type-B receptor 3; EPHB3; ETK2; HEK2; TYRO6 | |||||
200507 | EGFR | 200507 | P00533 | Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1 | |||||
200506 | DNA-PK | 200506 | P78527 | DNA-dependent protein kinase catalytic subunit | |||||
200505 | DDR1 | 200505 | Q08345 | Epithelial discoidin domain-containing receptor 1; discoidin domain receptor tyrosine kinase 1 | |||||
200504 | CSF1R | 200504 | P07333 | Macrophage colony-stimulating factor 1 receptor; colony stimulating factor 1 receptor | |||||
200503 | c-Raf | 200503 | P04049 | RAF proto-oncogene serine/threonine-protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1 | |||||
200555 | Src | 200555 | P12931 | Proto-oncogene tyrosine-protein kinase Src; V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); ASV; c-SRC; p60-Src; SRC; SRC1 | |||||
200502 | c-Met | 200502 | P08581 | Hepatocyte growth factor receptor; met proto-oncogene (hepatocyte growth factor receptor) | |||||
200501 | c-Kit | 200501 | P10721 | Mast/stem cell growth factor receptor Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | |||||
200500 | CHK2 | 200500 | O96017 | Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog | |||||
200559 | 1433G | 200559 | P61981 | 14-3-3 protein gamma | |||||
200560 | ABL(T315I) | 200560 | T315I | ||||||
200014 | ABL1(M351T) | 200014 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | M351T | |||
200002 | ABL1 | 200002 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | ||||
201419 | PIK3CA(H1047R) | 201419 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | H1047R | |||
200564 | TGFR1 | 200564 | P36897 | TGF-beta receptor type-1; ALK5 |