Proteins
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200018 | ABL1(Q252H)-phosphorylated | 200018 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Q252H | phosphorylated | Mutation (Q252H); Partial length | |
| 200016 | ABL1(Q252H) | 200016 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Q252H | |||
| 200332 | PIK3CA(Q546K) | 200332 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | Q546K | Mutation (Q546K); Partial length | ||
| 200174 | FLT3(R834Q) | 200174 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | R834Q | Mutation (R834Q); Partial length | ||
| 200132 | EGFR(S752-I759del) | 200132 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | S752-I759del | Mutation (S752-I759del); Partial length | ||
| 200179 | GCN2(Kin.Dom.2,S808G) | 200179 | Q9P2K8 | Eukaryotic translation initiation factor 2 alpha kinase 4; EIF2AK4; GCN2; KIAA1338 | KINOMEscan | S808G | Kin.Dom.2 | Wild Type; Partial length | |
| 200021 | ABL1(T315I)-phosphorylated | 200021 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | T315I | phosphorylated | Mutation (T315I); Partial length | |
| 200020 | ABL1(T315I)-nonphosphorylated | 200020 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | T315I | nonphosphorylated | Mutation (T315I); Partial length | |
| 200019 | ABL1(T315I) | 200019 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | T315I | |||
| 200560 | ABL(T315I) | 200560 | T315I | ||||||
| 200133 | EGFR(T790M) | 200133 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | T790M | Mutation (T790M); Partial length | ||
| 200219 | KIT(V559D) | 200219 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D | Mutation (V559D); Partial length | ||
| 200220 | KIT(V559D,T670I) | 200220 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D,T670I | Mutation (V559D,T670I); Partial length | ||
| 200221 | KIT(V559D,V654A) | 200221 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | V559D,V654A | Mutation (V559D,V654A); Partial length | ||
| 200055 | BRAF(V600E) | 200055 | P15056 | V-raf murine sarcoma viral oncogene homolog B1; BRAF; BRAF1; B-RAF1; FLJ95109; MGC126806; MGC138284; RAFB1 | KINOMEscan | V600E | Mutation (V600E); Partial length | ||
| 200568 | BRAF(V600E) | 200568 | P15056 | V-raf murine sarcoma viral oncogene homolog B1; BRAF; BRAF1; B-RAF1; FLJ95109; MGC126806; MGC138284; RAFB1 | V600E | ||||
| 200372 | RET(V804L) | 200372 | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET; RET51; RET-ELE1 | KINOMEscan | V804L | Mutation (V804L); Partial length | ||
| 200373 | RET(V804M) | 200373 | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET; RET51; RET-ELE1 | KINOMEscan | V804M | Mutation (V804M); Partial length | ||
| 200261 | MET(Y1235D) | 200261 | P08581 | Hepatocyte growth factor receptor; AUTS9; c-Met; HGFR; MET; RCCP2 | KINOMEscan | Y1235D | Mutation (Y1235D); Partial length | ||
| 200023 | ABL1(Y253F)-phosphorylated | 200023 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Y253F | phosphorylated | Mutation (Y253F); Partial length | |
| 200022 | ABL1(Y253F) | 200022 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Y253F | |||
| 200059 | BTK | 200059 | Q06187 | Tyrosine-protein kinase BTK; agammaglobulinemia tyrosine kinase; AGMX1; ATK; BPK | KINOMEscan | Wild Type; Full length | |||
| 200058 | BRSK2 | 200058 | Q8IWQ3 | BR serine/threonine kinase 2; BRSK2; C11orf7; FLJ41362; PEN11B; SAD1; STK29 | KINOMEscan | Wild Type; Full length | |||
| 200028 | ACVR1B | 200028 | P36896 | Activin A receptor, type IB; ACTRIB; ACVR1B; ACVRLK4; ALK4; SKR2 | KINOMEscan | Wild Type; Partial length | |||
| 200057 | BRSK1 | 200057 | Q8TDC3 | BR serine/threonine kinase 1; BRSK1; FLJ43009; KIAA1811 | KINOMEscan | Wild Type; Partial length |