Proteins

LINCS ID Name HMS LINCS ID UniProt ID Alternative Names Provider Mutation Phosphlorylation State Domain Protein Description
200514 FGFR1 200514 P11362
Fibroblast growth factor receptor 1
200517 GSK-3 beta 200517 P49841
Glycogen synthase kinase-3 beta; Serine/threonine-protein kinase GSK3B
200518 HSP90 200518
200520 IKKA 200520 O15111
Inhibitor of nuclear factor kappa-B kinase subunit alpha
200521 IKKB 200521 O14920
Inhibitor of nuclear factor kappa-B kinase subunit beta
201369 mTOR (pS2448) 201369 P42345 pS2448
200560 ABL(T315I) 200560 T315I
201367 GSK-3 alpha (pS21) 201367 P49840 pS21
200482 Akt-1 200482 P31749
RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha
200485 ALK 200485 Q9UM73
ALK tyrosine kinase receptor; anaplastic lymphoma receptor tyrosine kinase
200486 AMPK-alpha1 200486 Q13131
Protein kinase, AMP-activated, alpha 2 catalytic subunit
200488 ATM 200488 Q13315
Serine-protein kinase ATM
200489 Aurora kinase A 200489 O14965
Aurora 2; Aurora/IPL1-related kinase 1; ARK-1; Aurora-related kinase 1; hARK1; Breast tumor-amplified kinase; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; Serine/threonine-protein kinase aurora-A
200493 BCL2 200493 P10415
Apoptosis regulator Bcl-2
200494 BRAF 200494 P15056
Serine/threonine-protein kinase B-raf; v-raf murine sarcoma viral oncogene homolog B1; BRAF1; RAFB1
200496 CDC2 [deprecated record] 200496 P06493
Cyclin-dependent kinase 1
200534 MEKK3 200534 Q99759
Mitogen-activated protein kinase kinase kinase 3
200499 CHK1 200499 O14757
Serine/threonine-protein kinase Chk1; CHK1 checkpoint homolog
200500 CHK2 200500 O96017
Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog
200502 c-Met 200502 P08581
Hepatocyte growth factor receptor; met proto-oncogene (hepatocyte growth factor receptor)
200503 c-Raf 200503 P04049
RAF proto-oncogene serine/threonine-protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
200508 EPHB3 200508 P54753
Ephrin type-B receptor 3; EPHB3; ETK2; HEK2; TYRO6
200509 erbB-2 200509 P04626
Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD340
200526 JNK1 200526 P45983
Mitogen-activated protein kinase 8
200525 JAK3 200525 P52333
Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; L-JAK