Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| BT-20 | Sepantronium | 3.16 | -0.5677 | 0.58623 |
| BT-20 | Sepantronium | 9.992797406 | -0.5813 | 0.57603 |
| BT-20 | Sepantronium | 31.6 | -0.5379 | 0.57279 |
| BT-20 | Sepantronium | 50.0 | -0.5370 | 0.33012 |
| BT-20 | z-VAE(OMe)-fmk | 0.009992797 | 0.9685 | -0.00223 |
| BT-20 | z-VAE(OMe)-fmk | 0.0316 | 0.9680 | -0.00182 |
| BT-20 | z-VAE(OMe)-fmk | 0.099927974 | 1.0067 | -0.00772 |
| BT-20 | z-VAE(OMe)-fmk | 0.316 | 0.9697 | 0.00205 |
| BT-20 | z-VAE(OMe)-fmk | 0.999279741 | 1.0441 | 0.00694 |
| BT-20 | z-VAE(OMe)-fmk | 3.16 | 0.8938 | -0.00446 |
| BT-20 | z-VAE(OMe)-fmk | 9.992797406 | 0.9862 | -0.00524 |
| BT-20 | z-VAE(OMe)-fmk | 31.6 | 0.9762 | 0.00647 |
| BT-20 | z-VAE(OMe)-fmk | 50.0 | 1.0877 | -0.06126 |
| BT-549 | 1247825-37-1 | 0.009992797 | 1.0194 | -0.00500 |
| BT-549 | 1247825-37-1 | 0.0316 | 0.9965 | 0.00242 |
| BT-549 | 1247825-37-1 | 0.099927974 | 0.9858 | 0.00144 |
| BT-549 | 1247825-37-1 | 0.316 | 0.9922 | -0.00114 |
| BT-549 | 1247825-37-1 | 0.999279741 | 0.9971 | -0.00341 |
| BT-549 | 1247825-37-1 | 3.16 | 0.9749 | -0.00383 |
| BT-549 | 1247825-37-1 | 9.992797406 | 0.7654 | 0.00885 |
| BT-549 | 1247825-37-1 | 31.6 | -0.0124 | 0.16022 |
| BT-549 | 1247825-37-1 | 50.0 | -0.0465 | 0.18338 |
| BT-549 | b-AP15 | 0.009992797 | 1.0140 | 0.00397 |
| BT-549 | b-AP15 | 0.0316 | 0.9715 | -0.00522 |
| BT-549 | b-AP15 | 0.099927974 | 0.7099 | 0.02680 |