LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 40.10 | 11.8 | 1.6021 | 11.394 | -0.0635 | -1.0000 | 0.6554 | 0.2648 |
| MCF 10A-H2B-mCherry | Dasatinib | 42.07 | 11.8 | 1.5059 | 10.9559 | -0.0895 | -1.0000 | 0.6771 | 0.2737 |
| MCF 10A-H2B-mCherry | Dasatinib | 44.04 | 11.8 | 1.6363 | 11.3607 | -0.0896 | -1.0000 | 0.7451 | 0.2671 |
| MCF 10A-H2B-mCherry | Dasatinib | 46.00 | 11.8 | 1.925 | 11.0714 | -0.0764 | -1.0000 | 0.7940 | 0.2467 |
| MCF 10A-H2B-mCherry | Dasatinib | 47.98 | 11.8 | 2.0992 | 7.4506 | -0.1158 | -0.5961 | 1.9728 | 0.1935 |
| MCF 10A-H2B-mCherry | Dasatinib | 49.95 | 11.8 | 2.5744 | 6.7152 | -0.1544 | -0.6110 | 2.8420 | 0.1745 |
| MCF 10A-H2B-mCherry | Dasatinib | 51.92 | 11.8 | 3.0537 | 6.5874 | -0.1653 | -0.6311 | 2.9225 | 0.1678 |
| MCF 10A-H2B-mCherry | Dasatinib | 53.89 | 11.8 | 3.6067 | 4.3874 | -0.1243 | -0.2741 | 3.3297 | 0.1500 |
| MCF 10A-H2B-mCherry | Alpelisib | 72.62 | 11.8 | Inf | Inf | 0.1179 | 0.2602 | 0.5184 | 0.2709 |
| MCF 10A-H2B-mCherry | Alpelisib | 42.07 | 11.8 | Inf | Inf | 0.7930 | -0.0552 | 0.2023 | 0.0423 |
| MCF 10A-H2B-mCherry | Alpelisib | 74.59 | 11.8 | Inf | Inf | -0.2722 | -0.3540 | 0.4280 | 0.3853 |
| MCF 10A-H2B-mCherry | Etoposide | 24.34 | 11.8 | 0.8442 | 5.271 | 0.0105 | -0.5578 | 0.8577 | 0.3466 |
| MCF 10A-H2B-mCherry | Alpelisib | 76.56 | 11.8 | Inf | Inf | -0.3605 | -0.5430 | 0.4156 | 0.4223 |
| MCF 10A-H2B-mCherry | Alpelisib | 44.04 | 11.8 | Inf | Inf | 0.8807 | 0.2777 | 0.1810 | 0.0312 |
| MCF 10A-H2B-mCherry | Dasatinib | 68.68 | 11.8 | Inf | Inf | -0.4111 | -0.4111 | 0.0000 | 0.2388 |
| MCF 10A-H2B-mCherry | Dasatinib | 70.65 | 11.8 | Inf | Inf | -0.4702 | -0.7605 | 2.5000 | 0.2422 |
| MCF 10A-H2B-mCherry | Dasatinib | 72.62 | 11.8 | Inf | Inf | -0.6968 | -0.8679 | 2.5000 | 0.2828 |
| MCF 10A-H2B-mCherry | Dasatinib | 74.59 | 11.8 | Inf | Inf | -0.7935 | -0.7935 | 0.0000 | 0.3297 |
| MCF 10A-H2B-mCherry | Dasatinib | 76.56 | 11.8 | Inf | Inf | -0.7949 | -0.9180 | 2.5000 | 0.3265 |
| MCF 10A-H2B-mCherry | Dasatinib | 78.53 | 11.8 | Inf | Inf | -0.8878 | -0.9429 | 2.5000 | 0.3438 |
| MCF 10A-H2B-mCherry | Dasatinib | 80.50 | 11.8 | Inf | Inf | -0.9137 | -0.9137 | 0.0000 | 0.3813 |
| MCF 10A-H2B-mCherry | Dasatinib | 82.47 | 11.8 | Inf | Inf | -0.9461 | -0.9461 | 0.0000 | 0.4375 |
| MCF 10A-H2B-mCherry | Dasatinib | 84.44 | 11.8 | Inf | Inf | -0.9625 | -0.9625 | 0.0000 | 0.4367 |
| MCF 10A-H2B-mCherry | Dasatinib | 86.41 | 11.8 | Inf | Inf | -0.9407 | -0.9407 | 0.0000 | 0.4348 |
| MCF 10A-H2B-mCherry | Etoposide | 34.19 | 11.8 | 0.2149 | 0.2129 | -0.0119 | 0.0212 | 1.4114 | 0.4279 |