LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Alpelisib | 82.47 | 11.8 | Inf | Inf | -0.7155 | -0.9323 | 0.4722 | 0.5723 |
| MCF 10A-H2B-mCherry | Neratinib | 66.21 | 12.8 | 0.4418 | 0.7084 | -0.7114 | -0.8082 | 3.1712 | 0.3995 |
| MCF 10A-H2B-mCherry | Dasatinib | 72.62 | 11.8 | Inf | Inf | -0.6968 | -0.8679 | 2.5000 | 0.2828 |
| MCF 10A-H2B-mCherry | Taxol | 70.65 | 11.8 | Inf | Inf | -0.6937 | -0.7735 | 2.5000 | 1.0129 |
| MCF 10A-H2B-mCherry | Neratinib | 72.62 | 11.8 | Inf | Inf | -0.6829 | -0.9987 | 0.4021 | 0.4642 |
| MCF 10A-H2B-mCherry | Alpelisib | 84.44 | 11.8 | Inf | Inf | -0.6603 | -0.9436 | 0.4167 | 0.5697 |
| MCF 10A-H2B-mCherry | Taxol | 34.19 | 11.8 | 0.001 | 0.0016 | -0.6566 | -0.5868 | 1.8654 | 0.9446 |
| MCF 10A-H2B-mCherry | Taxol | 38.13 | 11.8 | 0.0009 | 0.0013 | -0.6497 | -0.5740 | 1.8740 | 0.9604 |
| MCF 10A-H2B-mCherry | Neratinib | 76.56 | 11.8 | Inf | Inf | -0.6488 | -0.9900 | 0.4587 | 0.4979 |
| MCF 10A-H2B-mCherry | Taxol | 36.16 | 11.8 | 0.0009 | 0.0015 | -0.6475 | -0.6132 | 1.7202 | 0.9852 |
| MCF 10A-H2B-mCherry | Etoposide | 78.53 | 11.8 | 0.4167 | 0.4886 | -0.6198 | -0.4902 | 4.5677 | 0.6156 |
| MCF 10A-H2B-mCherry | Etoposide | 82.47 | 11.8 | Inf | Inf | -0.6109 | -0.3921 | 2.5000 | 0.5753 |
| MCF 10A-H2B-mCherry | Etoposide | 80.50 | 11.8 | 0.4604 | 0.5628 | -0.5825 | -0.5212 | 4.2963 | 0.6204 |
| MCF 10A-H2B-mCherry | Alpelisib | 78.53 | 11.8 | Inf | Inf | -0.5687 | -0.7801 | 0.5348 | 0.5215 |
| MCF 10A-H2B-mCherry | Neratinib | 62.27 | 12.8 | 0.3897 | 0.5562 | -0.5658 | -0.5865 | 2.1736 | 0.3542 |
| MCF 10A-H2B-mCherry | Alpelisib | 86.41 | 11.8 | Inf | Inf | -0.5643 | -0.9298 | 0.3611 | 0.5327 |
| MCF 10A-H2B-mCherry | Alpelisib | 88.39 | 11.8 | Inf | Inf | -0.5245 | -0.9218 | 0.3023 | 0.5225 |
| MCF 10A-H2B-mCherry | Etoposide | 76.56 | 11.8 | Inf | Inf | -0.5161 | -0.3658 | 2.5000 | 0.6176 |
| MCF 10A-H2B-mCherry | Taxol | 88.39 | 11.8 | 0.0006 | 0.0007 | -0.5000 | -0.6119 | 5.0000 | 1.1071 |
| MCF 10A-H2B-mCherry | Taxol | 86.41 | 11.8 | 0.0006 | 0.0007 | -0.5000 | -0.5432 | 4.9994 | 1.0330 |
| MCF 10A-H2B-mCherry | Taxol | 84.44 | 11.8 | 0.0007 | 0.0008 | -0.5000 | -0.4460 | 5.0000 | 0.9331 |
| MCF 10A-H2B-mCherry | Taxol | 82.47 | 11.8 | 0.0008 | 0.0008 | -0.4992 | -0.3263 | 5.0000 | 0.8223 |
| MCF 10A-H2B-mCherry | Neratinib | 60.30 | 12.8 | 0.3735 | 0.4891 | -0.4937 | -0.4609 | 2.3613 | 0.3388 |
| MCF 10A-H2B-mCherry | Etoposide | 74.59 | 11.8 | Inf | Inf | -0.4921 | -0.3975 | 2.5000 | 0.6448 |
| MCF 10A-H2B-mCherry | Etoposide | 70.65 | 11.8 | 0.374 | 0.4184 | -0.4742 | -0.3943 | 5.0000 | 0.6342 |