LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 70.65 | 11.8 | Inf | Inf | -0.6937 | -0.7735 | 2.5000 | 1.0129 |
| MCF 10A-H2B-mCherry | Neratinib | 64.24 | 12.8 | 0.4495 | 0.6532 | -0.7536 | -0.7620 | 3.3315 | 0.3860 |
| MCF 10A-H2B-mCherry | Dasatinib | 70.65 | 11.8 | Inf | Inf | -0.4702 | -0.7605 | 2.5000 | 0.2422 |
| MCF 10A-H2B-mCherry | Palbociclib | 74.59 | 11.8 | 6.2258 | 8.3106 | -0.1752 | -0.7583 | 3.9365 | 0.1194 |
| MCF 10A-H2B-mCherry | Dasatinib | 66.21 | 12.8 | Inf | Inf | -0.3392 | -0.7266 | 2.5000 | 0.1746 |
| MCF 10A-H2B-mCherry | Taxol | 32.22 | 11.8 | 0.001 | 0.0019 | -0.8341 | -0.7201 | 1.5049 | 0.9893 |
| MCF 10A-H2B-mCherry | Dasatinib | 14.50 | 11.8 | 0.4949 | 9.8532 | 0.0959 | -0.7075 | 0.3145 | 0.4043 |
| MCF 10A-H2B-mCherry | Taxol | 62.27 | 12.8 | Inf | Inf | -0.4494 | -0.7005 | 2.5000 | 0.8507 |
| MCF 10A-H2B-mCherry | Taxol | 66.21 | 12.8 | Inf | Inf | -0.4158 | -0.6719 | 2.5000 | 0.8786 |
| MCF 10A-H2B-mCherry | Taxol | 60.30 | 12.8 | Inf | Inf | -0.3554 | -0.6653 | 2.5000 | 0.8293 |
| MCF 10A-H2B-mCherry | Palbociclib | 60.30 | 12.8 | 5.3415 | 7.9799 | 0.1640 | -0.6574 | 3.2998 | 0.1583 |
| MCF 10A-H2B-mCherry | Dasatinib | 18.43 | 11.8 | 0.3036 | 12.6517 | 0.0458 | -0.6348 | 0.3781 | 0.4299 |
| MCF 10A-H2B-mCherry | Dasatinib | 51.92 | 11.8 | 3.0537 | 6.5874 | -0.1653 | -0.6311 | 2.9225 | 0.1678 |
| MCF 10A-H2B-mCherry | Palbociclib | 78.53 | 11.8 | 6.8 | 7.9008 | -0.2637 | -0.6220 | 5.0000 | 0.0666 |
| MCF 10A-H2B-mCherry | Etoposide | 18.43 | 11.8 | 1.5522 | 7.8666 | 0.0158 | -0.6134 | 0.7772 | 0.2740 |
| MCF 10A-H2B-mCherry | Taxol | 36.16 | 11.8 | 0.0009 | 0.0015 | -0.6475 | -0.6132 | 1.7202 | 0.9852 |
| MCF 10A-H2B-mCherry | Taxol | 88.39 | 11.8 | 0.0006 | 0.0007 | -0.5000 | -0.6119 | 5.0000 | 1.1071 |
| MCF 10A-H2B-mCherry | Dasatinib | 49.95 | 11.8 | 2.5744 | 6.7152 | -0.1544 | -0.6110 | 2.8420 | 0.1745 |
| MCF 10A-H2B-mCherry | Dasatinib | 47.98 | 11.8 | 2.0992 | 7.4506 | -0.1158 | -0.5961 | 1.9728 | 0.1935 |
| MCF 10A-H2B-mCherry | Taxol | 64.24 | 12.8 | 0.0006 | 0.001 | -0.2726 | -0.5948 | 3.1044 | 0.9994 |
| MCF 10A-H2B-mCherry | Etoposide | 20.40 | 11.8 | 1.2916 | 6.3768 | -0.0004 | -0.5932 | 0.7629 | 0.2949 |
| MCF 10A-H2B-mCherry | Taxol | 34.19 | 11.8 | 0.001 | 0.0016 | -0.6566 | -0.5868 | 1.8654 | 0.9446 |
| MCF 10A-H2B-mCherry | Neratinib | 62.27 | 12.8 | 0.3897 | 0.5562 | -0.5658 | -0.5865 | 2.1736 | 0.3542 |
| MCF 10A-H2B-mCherry | Etoposide | 22.37 | 11.8 | 1.1454 | 4.6858 | -0.0123 | -0.5864 | 0.7803 | 0.3018 |
| MCF 10A-H2B-mCherry | Taxol | 38.13 | 11.8 | 0.0009 | 0.0013 | -0.6497 | -0.5740 | 1.8740 | 0.9604 |