LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Alpelisib | 36.16 | 11.8 | Inf | Inf | 0.7081 | 0.3588 | 0.1341 | 0.0812 |
| MCF 10A-H2B-mCherry | Palbociclib | 62.27 | 12.8 | Inf | Inf | 0.3703 | 0.3202 | 1.2436 | 0.0891 |
| MCF 10A-H2B-mCherry | Palbociclib | 70.65 | 11.8 | Inf | Inf | 0.3868 | 0.2469 | 2.5000 | 0.0899 |
| MCF 10A-H2B-mCherry | Alpelisib | 30.24 | 11.8 | Inf | Inf | 0.5895 | -0.1967 | 0.3776 | 0.1021 |
| MCF 10A-H2B-mCherry | Palbociclib | 88.39 | 11.8 | Inf | Inf | 0.1807 | 0.1415 | 2.5000 | 0.1081 |
| MCF 10A-H2B-mCherry | Palbociclib | 72.62 | 11.8 | Inf | Inf | 0.1477 | 0.0937 | 2.5000 | 0.1111 |
| MCF 10A-H2B-mCherry | Vorinostat | 66.21 | 12.8 | 3.8725 | 3.7635 | 0.0749 | 0.0914 | 5.0000 | 0.1148 |
| MCF 10A-H2B-mCherry | Alpelisib | 68.68 | 11.8 | Inf | Inf | 0.5890 | 0.7519 | 2.5000 | 0.1166 |
| MCF 10A-H2B-mCherry | Palbociclib | 68.68 | 11.8 | Inf | Inf | 0.2001 | 0.1415 | 2.5000 | 0.1170 |
| MCF 10A-H2B-mCherry | Dasatinib | 62.27 | 12.8 | 4.3975 | 5.6665 | -0.1761 | -0.4952 | 5.0000 | 0.1176 |
| MCF 10A-H2B-mCherry | Dasatinib | 64.24 | 12.8 | 7.076 | 8.823 | -0.3039 | -1.0000 | 5.0000 | 0.1184 |
| MCF 10A-H2B-mCherry | Palbociclib | 74.59 | 11.8 | 6.2258 | 8.3106 | -0.1752 | -0.7583 | 3.9365 | 0.1194 |
| MCF 10A-H2B-mCherry | Vorinostat | 62.27 | 12.8 | 3.9882 | 3.9503 | 0.0256 | 0.0310 | 5.0000 | 0.1237 |
| MCF 10A-H2B-mCherry | Dasatinib | 56.36 | 12.8 | 4.4755 | 5.1499 | -0.1439 | -0.2471 | 4.9992 | 0.1271 |
| MCF 10A-H2B-mCherry | Alpelisib | 28.28 | 11.8 | Inf | Inf | 0.5629 | -0.2183 | 0.2154 | 0.1305 |
| MCF 10A-H2B-mCherry | Dasatinib | 60.30 | 12.8 | 5.1736 | 6.2528 | -0.1534 | -0.4901 | 5.0000 | 0.1348 |
| MCF 10A-H2B-mCherry | Alpelisib | 26.31 | 11.8 | Inf | Inf | 0.5498 | -0.1965 | 0.2406 | 0.1366 |
| MCF 10A-H2B-mCherry | Dasatinib | 58.33 | 12.8 | 4.7813 | 6.0034 | -0.2173 | -0.5391 | 5.0000 | 0.1370 |
| MCF 10A-H2B-mCherry | Vorinostat | 68.68 | 11.8 | 4.1522 | 4.1031 | 0.0493 | 0.0341 | 5.0000 | 0.1469 |
| MCF 10A-H2B-mCherry | Dasatinib | 53.89 | 11.8 | 3.6067 | 4.3874 | -0.1243 | -0.2741 | 3.3297 | 0.1500 |
| MCF 10A-H2B-mCherry | Alpelisib | 24.34 | 11.8 | Inf | Inf | 0.5356 | -0.1945 | 0.3087 | 0.1509 |
| MCF 10A-H2B-mCherry | Palbociclib | 60.30 | 12.8 | 5.3415 | 7.9799 | 0.1640 | -0.6574 | 3.2998 | 0.1583 |
| MCF 10A-H2B-mCherry | Alpelisib | 22.37 | 11.8 | Inf | Inf | 0.5252 | 0.5693 | 2.5000 | 0.1619 |
| MCF 10A-H2B-mCherry | Alpelisib | 14.50 | 11.8 | Inf | Inf | 0.5830 | 0.5830 | 0.0000 | 0.1656 |
| MCF 10A-H2B-mCherry | Dasatinib | 51.92 | 11.8 | 3.0537 | 6.5874 | -0.1653 | -0.6311 | 2.9225 | 0.1678 |