LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Alpelisib | 44.04 | 11.8 | Inf | Inf | 0.8807 | 0.2777 | 0.1810 | 0.0312 |
| MCF 10A-H2B-mCherry | Alpelisib | 42.07 | 11.8 | Inf | Inf | 0.7930 | -0.0552 | 0.2023 | 0.0423 |
| MCF 10A-H2B-mCherry | Alpelisib | 40.10 | 11.8 | Inf | Inf | 0.7745 | 0.0032 | 0.1903 | 0.0455 |
| MCF 10A-H2B-mCherry | Alpelisib | 38.13 | 11.8 | Inf | Inf | 0.7322 | 0.2688 | 0.1564 | 0.0791 |
| MCF 10A-H2B-mCherry | Alpelisib | 36.16 | 11.8 | Inf | Inf | 0.7081 | 0.3588 | 0.1341 | 0.0812 |
| MCF 10A-H2B-mCherry | Alpelisib | 34.19 | 11.8 | Inf | Inf | 0.6682 | -0.1536 | 0.3663 | 0.0626 |
| MCF 10A-H2B-mCherry | Alpelisib | 32.22 | 11.8 | Inf | Inf | 0.6193 | -0.1765 | 0.3252 | 0.0795 |
| MCF 10A-H2B-mCherry | Alpelisib | 30.24 | 11.8 | Inf | Inf | 0.5895 | -0.1967 | 0.3776 | 0.1021 |
| MCF 10A-H2B-mCherry | Alpelisib | 28.28 | 11.8 | Inf | Inf | 0.5629 | -0.2183 | 0.2154 | 0.1305 |
| MCF 10A-H2B-mCherry | Alpelisib | 26.31 | 11.8 | Inf | Inf | 0.5498 | -0.1965 | 0.2406 | 0.1366 |
| MCF 10A-H2B-mCherry | Alpelisib | 24.34 | 11.8 | Inf | Inf | 0.5356 | -0.1945 | 0.3087 | 0.1509 |
| MCF 10A-H2B-mCherry | Alpelisib | 22.37 | 11.8 | Inf | Inf | 0.5252 | 0.5693 | 2.5000 | 0.1619 |
| MCF 10A-H2B-mCherry | Alpelisib | 20.40 | 11.8 | Inf | Inf | 0.5314 | 0.5864 | 2.4995 | 0.1792 |
| MCF 10A-H2B-mCherry | Alpelisib | 18.43 | 11.8 | Inf | Inf | 0.5222 | 0.6101 | 2.4994 | 0.1797 |
| MCF 10A-H2B-mCherry | Alpelisib | 16.47 | 11.8 | Inf | Inf | 0.5437 | 0.5437 | 0.0000 | 0.1861 |
| MCF 10A-H2B-mCherry | Vorinostat | 72.62 | 11.8 | Inf | Inf | 0.1396 | 0.1396 | 0.0000 | 0.1845 |
| MCF 10A-H2B-mCherry | Vorinostat | 74.59 | 11.8 | Inf | Inf | 0.0392 | 0.0407 | 2.5000 | 0.2224 |
| MCF 10A-H2B-mCherry | Vorinostat | 76.56 | 11.8 | Inf | Inf | 0.2240 | 0.1921 | 2.5000 | 0.2324 |
| MCF 10A-H2B-mCherry | Vorinostat | 78.53 | 11.8 | Inf | Inf | 0.0626 | 0.1037 | 2.4991 | 0.2671 |
| MCF 10A-H2B-mCherry | Vorinostat | 80.50 | 11.8 | Inf | Inf | 0.2547 | 0.2547 | 0.0000 | 0.2783 |
| MCF 10A-H2B-mCherry | Vorinostat | 82.47 | 11.8 | Inf | Inf | 0.2104 | 0.1892 | 2.5000 | 0.2370 |
| MCF 10A-H2B-mCherry | Vorinostat | 84.44 | 11.8 | Inf | Inf | 0.0363 | -0.0010 | 2.5000 | 0.2746 |
| MCF 10A-H2B-mCherry | Vorinostat | 86.41 | 11.8 | Inf | Inf | 0.1733 | 0.1489 | 2.5000 | 0.2719 |
| MCF 10A-H2B-mCherry | Palbociclib | 22.37 | 11.8 | Inf | Inf | 0.0799 | 0.0010 | 0.2557 | 0.3981 |
| MCF 10A-H2B-mCherry | Vorinostat | 88.39 | 11.8 | Inf | Inf | 0.1389 | 0.0902 | 2.5000 | 0.4167 |