LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 82.47 | 11.8 | Inf | Inf | -0.6109 | -0.3921 | 2.5000 | 0.5753 |
| MCF 10A-H2B-mCherry | Etoposide | 76.56 | 11.8 | Inf | Inf | -0.5161 | -0.3658 | 2.5000 | 0.6176 |
| MCF 10A-H2B-mCherry | Trametinib | 14.50 | 11.8 | Inf | Inf | 0.6020 | 0.6432 | 0.3547 | 0.2812 |
| MCF 10A-H2B-mCherry | Trametinib | 16.47 | 11.8 | Inf | Inf | 0.4895 | 0.5143 | 0.2747 | 0.3240 |
| MCF 10A-H2B-mCherry | Etoposide | 74.59 | 11.8 | Inf | Inf | -0.4921 | -0.3975 | 2.5000 | 0.6448 |
| MCF 10A-H2B-mCherry | Etoposide | 72.62 | 11.8 | Inf | Inf | -0.4368 | -0.3631 | 2.5000 | 0.6217 |
| MCF 10A-H2B-mCherry | Etoposide | 68.68 | 11.8 | Inf | Inf | -0.3486 | -0.3917 | 2.4998 | 0.6419 |
| MCF 10A-H2B-mCherry | Etoposide | 66.21 | 12.8 | Inf | Inf | -0.2675 | -0.3004 | 2.4999 | 0.5759 |
| MCF 10A-H2B-mCherry | Etoposide | 64.24 | 12.8 | Inf | Inf | -0.1610 | -0.2439 | 2.5000 | 0.6044 |
| MCF 10A-H2B-mCherry | Etoposide | 62.27 | 12.8 | Inf | Inf | -0.0470 | -0.0653 | 2.5000 | 0.5949 |
| MCF 10A-H2B-mCherry | Etoposide | 60.30 | 12.8 | Inf | Inf | -0.0882 | -0.1344 | 2.5000 | 0.6136 |
| MCF 10A-H2B-mCherry | Dasatinib | 88.39 | 11.8 | Inf | Inf | -0.9411 | -0.9411 | 0.0000 | 0.4784 |
| MCF 10A-H2B-mCherry | Dasatinib | 86.41 | 11.8 | Inf | Inf | -0.9407 | -0.9407 | 0.0000 | 0.4348 |
| MCF 10A-H2B-mCherry | Dasatinib | 84.44 | 11.8 | Inf | Inf | -0.9625 | -0.9625 | 0.0000 | 0.4367 |
| MCF 10A-H2B-mCherry | Dasatinib | 82.47 | 11.8 | Inf | Inf | -0.9461 | -0.9461 | 0.0000 | 0.4375 |
| MCF 10A-H2B-mCherry | Dasatinib | 80.50 | 11.8 | Inf | Inf | -0.9137 | -0.9137 | 0.0000 | 0.3813 |
| MCF 10A-H2B-mCherry | Dasatinib | 78.53 | 11.8 | Inf | Inf | -0.8878 | -0.9429 | 2.5000 | 0.3438 |
| MCF 10A-H2B-mCherry | Dasatinib | 76.56 | 11.8 | Inf | Inf | -0.7949 | -0.9180 | 2.5000 | 0.3265 |
| MCF 10A-H2B-mCherry | Dasatinib | 74.59 | 11.8 | Inf | Inf | -0.7935 | -0.7935 | 0.0000 | 0.3297 |
| MCF 10A-H2B-mCherry | Dasatinib | 72.62 | 11.8 | Inf | Inf | -0.6968 | -0.8679 | 2.5000 | 0.2828 |
| MCF 10A-H2B-mCherry | Dasatinib | 70.65 | 11.8 | Inf | Inf | -0.4702 | -0.7605 | 2.5000 | 0.2422 |
| MCF 10A-H2B-mCherry | Dasatinib | 68.68 | 11.8 | Inf | Inf | -0.4111 | -0.4111 | 0.0000 | 0.2388 |
| MCF 10A-H2B-mCherry | Dasatinib | 66.21 | 12.8 | Inf | Inf | -0.3392 | -0.7266 | 2.5000 | 0.1746 |
| MCF 10A-H2B-mCherry | Alpelisib | 14.50 | 11.8 | Inf | Inf | 0.5830 | 0.5830 | 0.0000 | 0.1656 |
| MCF 10A-H2B-mCherry | Alpelisib | 88.39 | 11.8 | Inf | Inf | -0.5245 | -0.9218 | 0.3023 | 0.5225 |