LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Vorinostat | 32.22 | 11.8 | 0.9059 | 1.1627 | -0.1790 | -0.2162 | 1.5077 | 0.3493 |
| MCF 10A-H2B-mCherry | Vorinostat | 34.19 | 11.8 | 0.9662 | 1.1637 | -0.1728 | -0.1799 | 1.7595 | 0.3409 |
| MCF 10A-H2B-mCherry | Vorinostat | 36.16 | 11.8 | 0.9912 | 1.2763 | -0.1517 | -0.2171 | 1.5287 | 0.3504 |
| MCF 10A-H2B-mCherry | Vorinostat | 38.13 | 11.8 | 1.0933 | 1.5334 | -0.1393 | -0.2543 | 1.4988 | 0.3379 |
| MCF 10A-H2B-mCherry | Vorinostat | 40.10 | 11.8 | 1.1886 | 1.5665 | -0.1579 | -0.2294 | 1.6202 | 0.3079 |
| MCF 10A-H2B-mCherry | Vorinostat | 42.07 | 11.8 | 1.285 | 1.6088 | -0.1099 | -0.1795 | 1.7569 | 0.2922 |
| MCF 10A-H2B-mCherry | Vorinostat | 44.04 | 11.8 | 1.3459 | 1.5822 | -0.0929 | -0.1342 | 2.2818 | 0.2916 |
| MCF 10A-H2B-mCherry | Vorinostat | 46.00 | 11.8 | 1.5115 | 1.711 | -0.0737 | -0.1019 | 2.8555 | 0.2966 |
| MCF 10A-H2B-mCherry | Vorinostat | 47.98 | 11.8 | 1.6757 | 1.804 | -0.0844 | -0.0433 | 3.4402 | 0.2717 |
| MCF 10A-H2B-mCherry | Vorinostat | 49.95 | 11.8 | 1.7933 | 1.8862 | -0.0877 | -0.0193 | 3.5303 | 0.2968 |
| MCF 10A-H2B-mCherry | Vorinostat | 51.92 | 11.8 | 2.1315 | 2.1375 | -0.0749 | 0.0429 | 3.8157 | 0.2783 |
| MCF 10A-H2B-mCherry | Vorinostat | 53.89 | 11.8 | 2.3205 | 2.3162 | -0.0685 | 0.0560 | 4.1745 | 0.3126 |
| MCF 10A-H2B-mCherry | Vorinostat | 56.36 | 12.8 | 2.7127 | 2.6256 | -0.1112 | 0.0745 | 4.1340 | 0.2855 |
| MCF 10A-H2B-mCherry | Vorinostat | 58.33 | 12.8 | 3.121 | 3.2846 | -0.0803 | -0.0654 | 4.1663 | 0.2100 |
| MCF 10A-H2B-mCherry | Vorinostat | 60.30 | 12.8 | 3.0037 | 3.1465 | -0.0371 | -0.0795 | 3.9007 | 0.2301 |
| MCF 10A-H2B-mCherry | Vorinostat | 62.27 | 12.8 | 3.9882 | 3.9503 | 0.0256 | 0.0310 | 5.0000 | 0.1237 |
| MCF 10A-H2B-mCherry | Vorinostat | 64.24 | 12.8 | 3.8453 | 3.8311 | 0.0082 | 0.0174 | 5.0000 | 0.1712 |
| MCF 10A-H2B-mCherry | Vorinostat | 66.21 | 12.8 | 3.8725 | 3.7635 | 0.0749 | 0.0914 | 5.0000 | 0.1148 |
| MCF 10A-H2B-mCherry | Vorinostat | 68.68 | 11.8 | 4.1522 | 4.1031 | 0.0493 | 0.0341 | 5.0000 | 0.1469 |
| MCF 10A-H2B-mCherry | Vorinostat | 70.65 | 11.8 | 4.0002 | 3.6262 | 0.0895 | 0.1990 | 4.9999 | 0.1728 |
| MCF 10A-H2B-mCherry | Vorinostat | 72.62 | 11.8 | Inf | Inf | 0.1396 | 0.1396 | 0.0000 | 0.1845 |
| MCF 10A-H2B-mCherry | Vorinostat | 74.59 | 11.8 | Inf | Inf | 0.0392 | 0.0407 | 2.5000 | 0.2224 |
| MCF 10A-H2B-mCherry | Vorinostat | 76.56 | 11.8 | Inf | Inf | 0.2240 | 0.1921 | 2.5000 | 0.2324 |
| MCF 10A-H2B-mCherry | Vorinostat | 78.53 | 11.8 | Inf | Inf | 0.0626 | 0.1037 | 2.4991 | 0.2671 |
| MCF 10A-H2B-mCherry | Vorinostat | 80.50 | 11.8 | Inf | Inf | 0.2547 | 0.2547 | 0.0000 | 0.2783 |