LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 9 of 15: End-point dose-response metrics for biological replicate 3. - Dataset (ID:20317)
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| Cell | Small Molecule | Time Point (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 72 | 0.5612 | 1.2244 | 0.1419 | -0.2015 | 0.4341 | 0.3610 |
| MCF 10A-H2B-mCherry | Vorinostat | 72 | 0.8282 | 1.127 | -0.0873 | -0.2023 | 1.1031 | 0.3632 |
| MCF 10A-H2B-mCherry | Vorinostat | 60 | 0.7223 | 1.0618 | -0.0810 | -0.2268 | 0.9711 | 0.3866 |
| MCF 10A-H2B-mCherry | Vorinostat | 48 | 0.6114 | 0.9444 | -0.0821 | -0.2429 | 0.9107 | 0.4110 |
| MCF 10A-H2B-mCherry | Taxol | 60 | 0.0011 | 0.0014 | -0.3195 | -0.2487 | 1.3756 | 0.7703 |
| MCF 10A-H2B-mCherry | Vorinostat | 36 | 0.554 | 0.9298 | -0.0652 | -0.2551 | 0.7961 | 0.4258 |
| MCF 10A-H2B-mCherry | Taxol | 72 | 0.001 | 0.0013 | -0.3180 | -0.2585 | 1.4036 | 0.7880 |
| MCF 10A-H2B-mCherry | Taxol | 48 | 0.0013 | 0.0019 | -0.3312 | -0.2815 | 1.1758 | 0.7519 |
| MCF 10A-H2B-mCherry | Taxol | 84 | 0.0009 | 0.0012 | -0.3444 | -0.2890 | 1.3812 | 0.8153 |
| MCF 10A-H2B-mCherry | Taxol | 36 | 0.0017 | 0.0028 | -0.3238 | -0.3277 | 0.9300 | 0.7159 |
| MCF 10A-H2B-mCherry | Palbociclib | 36 | 8.2546 | 999.9626 | 0.4151 | -0.4519 | 0.1342 | 0.3252 |
| MCF 10A-H2B-mCherry | Vorinostat | 24 | 0.4754 | 1.7724 | -0.0276 | -0.4821 | 0.5130 | 0.4423 |
| MCF 10A-H2B-mCherry | Taxol | 24 | 0.002 | 0.0084 | -0.2083 | -0.5081 | 0.4902 | 0.6573 |
| MCF 10A-H2B-mCherry | Palbociclib | 48 | 3.3346 | 999.9941 | 0.3630 | -0.7979 | 0.1673 | 0.3254 |
| MCF 10A-H2B-mCherry | Etoposide | 60 | 0.847 | 16.3367 | 0.1412 | -0.8621 | 0.3387 | 0.3416 |
| MCF 10A-H2B-mCherry | Dasatinib | 36 | 1.8278 | 999.8676 | 0.3368 | -0.9426 | 0.1681 | 0.3611 |
| MCF 10A-H2B-mCherry | Dasatinib | 60 | 1.0757 | 102.3859 | 0.1735 | -1.0000 | 0.2412 | 0.3555 |
| MCF 10A-H2B-mCherry | Dasatinib | 48 | 1.2987 | 299.0185 | 0.3294 | -1.0000 | 0.2020 | 0.3592 |
| MCF 10A-H2B-mCherry | Neratinib | 48 | 0.1895 | 4.5797 | 0.0307 | -1.0000 | 0.3449 | 0.3845 |
| MCF 10A-H2B-mCherry | Etoposide | 48 | 1.1834 | 37.3253 | 0.1896 | -1.0000 | 0.3183 | 0.3192 |
| MCF 10A-H2B-mCherry | Neratinib | 84 | 0.2629 | 2.4045 | -0.1966 | -1.0000 | 0.4964 | 0.3709 |
| MCF 10A-H2B-mCherry | Palbociclib | 60 | 2.6707 | 808.9177 | 0.3136 | -1.0000 | 0.1923 | 0.3179 |
| MCF 10A-H2B-mCherry | Neratinib | 72 | 0.246 | 2.6692 | -0.1124 | -1.0000 | 0.4607 | 0.3588 |
| MCF 10A-H2B-mCherry | Palbociclib | 72 | 2.3133 | 319.7903 | 0.2433 | -1.0000 | 0.2229 | 0.3116 |
| MCF 10A-H2B-mCherry | Palbociclib | 84 | 2.3696 | 134.4749 | 0.1665 | -1.0000 | 0.2720 | 0.2965 |