LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 7 of 15: End-point dose-response metrics for biological replicate 1. - Dataset (ID:20315)

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Cell Small Molecule Time Point (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Trametinib 14
Inf
 0.0076 0.7513 0.8546 4.9986 0.0689
MCF 10A-H2B-mCherry Alpelisib 14
Inf
 1.3563 0.7546 0.8330 4.9988 0.0207
MCF 10A-H2B-mCherry Alpelisib 25
Inf
 1.4330 0.6573 0.7499 5.0000 0.0556
MCF 10A-H2B-mCherry Neratinib 14
Inf
 0.0623 0.5705 0.6446 5.0000 0.1630
MCF 10A-H2B-mCherry Palbociclib 14
Inf
 0.0470 0.6055 0.6286 2.3771 0.2335
MCF 10A-H2B-mCherry Trametinib 25
0.0129
 0.0032 0.4248 0.4682 1.9686 0.3579
MCF 10A-H2B-mCherry Dasatinib 25
0.7437
 0.2076 0.2558 0.3396 0.8909 0.2675
MCF 10A-H2B-mCherry Neratinib 25
0.0623
 0.0324 0.3130 0.3244 1.6032 0.3411
MCF 10A-H2B-mCherry Trametinib 36
0.0058
 0.0031 0.2898 0.3109 1.5832 0.4664
MCF 10A-H2B-mCherry Palbociclib 25
0.1608
 0.0623 0.3195 0.3100 1.0196 0.4040
MCF 10A-H2B-mCherry Trametinib 49
0.0066
 0.0040 0.2185 0.2369 1.2900 0.4933
MCF 10A-H2B-mCherry Palbociclib 36
0.216
 0.1111 0.2237 0.2190 0.8662 0.3977
MCF 10A-H2B-mCherry Trametinib 60
0.0078
 0.0050 0.1929 0.2064 1.1997 0.4918
MCF 10A-H2B-mCherry Neratinib 36
0.0691
 0.0508 0.1855 0.1913 1.5671 0.3705
MCF 10A-H2B-mCherry Palbociclib 49
0.2432
 0.1490 0.1924 0.1866 0.9531 0.3867
MCF 10A-H2B-mCherry Trametinib 74
0.0093
 0.0062 0.1778 0.1846 1.1445 0.4863
MCF 10A-H2B-mCherry Trametinib 85
0.0112
 0.0077 0.1723 0.1730 1.1413 0.4734
MCF 10A-H2B-mCherry Palbociclib 60
0.308
 0.1983 0.1719 0.1611 0.8830 0.3696
MCF 10A-H2B-mCherry Palbociclib 74
0.3799
 0.2585 0.1562 0.1383 0.8411 0.3557
MCF 10A-H2B-mCherry Vorinostat 14
1.2267
 0.9430 0.1980 0.1308 1.1529 0.2691
MCF 10A-H2B-mCherry Neratinib 49
0.1003
 0.0824 0.1199 0.1213 1.4136 0.3576
MCF 10A-H2B-mCherry Palbociclib 85
0.4752
 0.3445 0.1455 0.1140 0.8049 0.3379
MCF 10A-H2B-mCherry Dasatinib 36
0.7304
 0.5300 0.1489 0.0939 0.6483 0.2962
MCF 10A-H2B-mCherry Neratinib 60
0.1262
 0.1133 0.0711 0.0699 1.4052 0.3452
MCF 10A-H2B-mCherry Etoposide 14
0.9278
 0.8558 0.0750 0.0630 1.6679 0.2602
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