LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 2.70 | 19.50 | 198 | 163 | 1.1873 | 0.5064 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.031667 | 2.70 | 19.50 | 198 | 163 | 1.1980 | 0.5324 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.1 | 2.70 | 19.50 | 199 | 163 | 1.2200 | 0.5600 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 59.80 | 19.50 | 199 | 5578 | 0.0352 | 0.0242 |
| MCF 10A-H2B-mCherry | Taxol | 0.1 | 2.70 | 19.50 | 199 | 163 | 1.2004 | 0.5475 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 2.70 | 19.50 | 199 | 163 | 1.2128 | 0.5171 |
| MCF 10A-H2B-mCherry | 0 | 2.70 | 19.50 | 199 | 163 | 1.2297 | 0.5386 | |
| MCF 10A-H2B-mCherry | Etoposide | 0.56234 | 2.70 | 19.50 | 200 | 163 | 1.2808 | 0.5278 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.018333 | 2.70 | 19.50 | 200 | 163 | 1.2299 | 0.5744 |
| MCF 10A-H2B-mCherry | Taxol | 0.1 | 12.50 | 19.50 | 200 | 495 | 0.4040 | 0.3203 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 2.70 | 19.50 | 201 | 163 | 1.2356 | 0.5243 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.56234 | 2.70 | 19.50 | 201 | 163 | 1.2065 | 0.5139 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 55.90 | 19.50 | 204 | 5348 | 0.0379 | 0.0523 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 57.80 | 19.50 | 204 | 5483 | 0.0361 | 0.0342 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 16.50 | 19.50 | 205 | 626 | 0.3338 | 0.1898 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 2.70 | 19.50 | 206 | 163 | 1.2611 | 0.6092 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0033333 | 2.70 | 19.50 | 206 | 163 | 1.2324 | 0.5411 |
| MCF 10A-H2B-mCherry | Neratinib | 0.01 | 2.70 | 19.50 | 206 | 163 | 1.2722 | 0.5774 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 12.50 | 19.50 | 207 | 495 | 0.4181 | 0.2488 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 84.40 | 19.50 | 207 | 6038 | 0.0346 | 0.0272 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 80.50 | 19.50 | 207 | 6018 | 0.0350 | 0.0388 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 82.50 | 19.50 | 207 | 6031 | 0.0349 | 0.0360 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 18.40 | 19.50 | 208 | 775 | 0.2699 | 0.2242 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 2.70 | 19.50 | 210 | 163 | 1.3018 | 0.5945 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 2.70 | 19.50 | 211 | 163 | 1.2381 | 0.5116 |